The concept of phase-separation-mediated formation of biomolecular condensates provides
a new framework to understand cellular organization and cooperativity-dependent cellular …

Current technologies have changed biology into a data-intensive field and significantly
increased our understanding of signal transduction pathways in plants. However, global …

In the light of the current coronavirus crisis, business-to-business firms face a variety of
challenges in a complex and fast-changing environment. In order to provide structured …

Genome-scale metabolic models are instrumental in uncovering operating principles of
cellular metabolism, for model-guided re-engineering, and unraveling cross-feeding in …

Although it is broadly agreed that the improved treatment of patients with cancer will depend
on a deeper molecular understanding of the underlying pathogenesis, only a few examples …

Recent structural studies of receptor tyrosine kinases (RTKs) have revealed unexpected
diversity in the mechanisms of their activation by growth factor ligands. Strategies for …

First discovered in Drosophila, the Hippo signaling pathway is a conserved regulator of
organ size. Central to this pathway is a kinase cascade leading from the tumor suppressor …

Abstract “Neural plasticity” refers to the capacity of the nervous system to modify itself,
functionally and structurally, in response to experience and injury. As the various chapters in …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Alzheimer's disease (AD) starts from pure cognitive impairments and gradually progresses
into degeneration of specific brain circuits. Although numerous factors initiating AD have …