Lipolysis: cellular mechanisms for lipid mobilization from fat stores

GF Grabner, H **e, M Schweiger, R Zechner - Nature metabolism, 2021 - nature.com
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

Growth hormone and insulin-like growth factor 1 regulation of nonalcoholic fatty liver disease

LE Dichtel, J Cordoba-Chacon… - The Journal of Clinical …, 2022 - academic.oup.com
Patients with obesity have a high prevalence of nonalcoholic fatty liver disease (NAFLD),
representing a spectrum of simple steatosis to nonalcoholic steatohepatitis (NASH), without …

Important hormones regulating lipid metabolism

D Zhang, Y Wei, Q Huang, Y Chen, K Zeng, W Yang… - Molecules, 2022 - mdpi.com
There is a wide variety of kinds of lipids, and complex structures which determine the
diversity and complexity of their functions. With the basic characteristic of water insolubility …

[HTML][HTML] Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks

E Rendina-Ruedy, CJ Rosen - Molecular metabolism, 2022 - Elsevier
Background Late in the nineteenth century, it was theorized that a circulating product
produced by the parathyroid glands could negatively impact skeletal homeostasis. A century …

New findings on brain actions of growth hormone and potential clinical implications

J Donato Jr, JJ Kopchick - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
Growth hormone (GH) is secreted by somatotropic cells of the anterior pituitary gland. The
classical effects of GH comprise the stimulation of cell proliferation, tissue and body growth …

Covert actions of growth hormone: fibrosis, cardiovascular diseases and cancer

JJ Kopchick, R Basu, DE Berryman… - Nature Reviews …, 2022 - nature.com
Since its discovery nearly a century ago, over 100,000 studies of growth hormone (GH) have
investigated its structure, how it interacts with the GH receptor and its multiple actions. These …

Progress in nanoparticle-based electrochemical biosensors for hormone detection

F Rossi, T Trakoolwilaiwan, V Gigli, C Tortolini, A Lenzi… - Nanoscale, 2024 - pubs.rsc.org
Hormones are chemical messengers that regulate a wide range of physiological processes
including metabolism, development, growth, reproduction and mood. The concentration of …

Growth hormone receptor gene disruption in mature‐adult mice improves male insulin sensitivity and extends female lifespan

S Duran‐Ortiz, EO List, Y Ikeno, J Young, R Basu… - Aging cell, 2021 - Wiley Online Library
Studies in multiple species indicate that reducing growth hormone (GH) action enhances
healthy lifespan. In fact, GH receptor knockout (GHRKO) mice hold the Methuselah prize for …

The effects of nutrition on linear growth

E Inzaghi, V Pampanini, A Deodati, S Cianfarani - Nutrients, 2022 - mdpi.com
Linear growth is a complex process and is considered one of the best indicators of children's
well-being and health. Genetics, epigenetics and environment (mainly stress and availability …

Effect of growth hormone on insulin signaling

R Sharma, JJ Kopchick, V Puri, VM Sharma - Molecular and cellular …, 2020 - Elsevier
Growth hormone (GH) is a pleiotropic hormone that coordinates an array of physiological
processes, including effects on bone, muscle, and fat, ultimately resulting in growth …