Multivalent proteins and nucleic acids, collectively referred to as multivalent associative
biomacromolecules, provide the driving forces for the formation and compositional …

AUosteric proteins control and coordinate chemical events in the living cell. When Monod
conceived that idea he said that he had discovered the second secret of life. The first was …

Ligand-macromolecule interactions are of fundamental importance in the control of
biological processes. This book applies the principles of linkage thermodynamics to …

Publisher Summary This chapter provides a compact introduction of hemocyanins. Its
synthesis and evolution is also discussed. Hemocyanins are transport proteins. In these …

The ability to transport oxygen is a key biological process in multicellular organisms. Three
general classes of respiratory proteins have evolved: hemoglobins, hemerythrins, and …

Revised Manuscript Received March 8, 1995® abstract: Initial rates of ATP hydrolysis by
wild-type GroEL were measured as a function of ATP concentration from 0 to 0.8 mM. Two …

This review summarizes recent highlights of our joint work on the structure, evolution, and
function of a family of highly complex proteins, the hemocyanins. They are blue-pigmented …

Hemocyanin is an extracellular, blue protein that occurs in high concentrations in the blood
of many arthropods, including spiders, scorpions, horseshoe crabs, crustaceans, and at …

The Hill functions, H h (x)= xh/(1+ xh), have been widely used in biology for over a century
but, with the exception of H 1, they have had no justification other than as a convenient fit to …

Integration of binding information by macromolecular entities is fundamental to cellular
functionality. Recent work has shown that such integration cannot be explained by pairwise …