Background and aims Alcohol use is a major contributor to injuries, mortality and the burden
of disease. This review updates knowledge on risk relations between dimensions of alcohol …

In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …

Cirrhosis is an increasing cause of morbidity and mortality in more developed countries,
being the 14th most common cause of death worldwide but fourth in central Europe …

The harmful use of alcohol has been estimated to cause approximately 3.3 million deaths
every year, corresponding to nearly 6% of all deaths globally. Therefore, the effective …

Excessive alcohol consumption is a global healthcare problem. The liver sustains the
greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol …

CLD s represent an important, and certainly underestimated, global public health problem.
CLD s are highly prevalent and silent, related to different, sometimes associated causes …

Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

Alcoholic liver disease (ALD) is a complex process that includes a wide spectrum of hepatic
lesions, from steatosis to cirrhosis. Cell injury, inflammation, oxidative stress, regeneration …

Background Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver
impairment that occurs in patients with a history of heavy and prolonged alcohol use. The …

Liver diseases contribute markedly to the global burden of mortality and disease. This paper
provides an overview from a global perspective of the contribution of alcohol to liver …