Encouraging an excitable brain state: mechanisms of brain repair in stroke

MT Joy, ST Carmichael - Nature Reviews Neuroscience, 2021 - nature.com
Stroke induces a plastic state in the brain. This period of enhanced plasticity leads to the
sprouting of new axons, the formation of new synapses and the remap** of sensory-motor …

Modulation of brain plasticity in stroke: a novel model for neurorehabilitation

G Di Pino, G Pellegrino, G Assenza, F Capone… - Nature Reviews …, 2014 - nature.com
Noninvasive brain stimulation (NIBS) techniques can be used to monitor and modulate the
excitability of intracortical neuronal circuits. Long periods of cortical stimulation can produce …

[HTML][HTML] CCR5 is a therapeutic target for recovery after stroke and traumatic brain injury

MT Joy, EB Assayag, D Shabashov-Stone… - Cell, 2019 - cell.com
We tested a newly described molecular memory system, CCR5 signaling, for its role in
recovery after stroke and traumatic brain injury (TBI). CCR5 is uniquely expressed in cortical …

Inter-individual variability in response to non-invasive brain stimulation paradigms

V López-Alonso, B Cheeran, D Río-Rodríguez… - Brain stimulation, 2014 - Elsevier
Abstract Background Non-invasive Brain Stimulation (NIBS) paradigms are unique in their
ability to safely modulate cortical plasticity for experimental or therapeutic applications …

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke

AN Clarkson, BS Huang, SE MacIsaac, I Mody… - Nature, 2010 - nature.com
Stroke is a leading cause of disability, but no pharmacological therapy is currently available
for promoting recovery. The brain region adjacent to stroke damage—the peri-infarct zone …

Neuroplastic changes following brain ischemia and their contribution to stroke recovery: novel approaches in neurorehabilitation

C Alia, C Spalletti, S Lai, A Panarese… - Frontiers in cellular …, 2017 - frontiersin.org
Ischemic damage to the brain triggers substantial reorganization of spared areas and
pathways, which is associated with limited, spontaneous restoration of function. A better …

Rehabilitation with poststroke motor recovery: a review with a focus on neural plasticity

N Takeuchi, SI Izumi - Stroke research and treatment, 2013 - Wiley Online Library
Motor recovery after stroke is related to neural plasticity, which involves develo** new
neuronal interconnections, acquiring new functions, and compensating for impairment …

Anodal transcranial direct current stimulation boosts synaptic plasticity and memory in mice via epigenetic regulation of Bdnf expression

MV Podda, S Cocco, A Mastrodonato, S Fusco… - Scientific reports, 2016 - nature.com
The effects of transcranial direct current stimulation (tDCS) on brain functions and the
underlying molecular mechanisms are yet largely unknown. Here we report that mice …

Prediction of recovery of motor function after stroke

C Stinear - The Lancet Neurology, 2010 - thelancet.com
Background Stroke is a leading cause of disability. The ability to live independently after
stroke depends largely on the reduction of motor impairment and the recovery of motor …

Rehabilitation of upper limb motor impairment in stroke: a narrative review on the prevalence, risk factors, and economic statistics of stroke and state of the art …

S Anwer, A Waris, SO Gilani, J Iqbal, N Shaikh… - Healthcare, 2022 - mdpi.com
Stroke has been one of the leading causes of disability worldwide and is still a social health
issue. Kee** in view the importance of physical rehabilitation of stroke patients, an …