Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …

Neuropeptides are found in many mammalian CNS neurons where they play key roles in
modulating neuronal activity. In contrast to amino acid transmitter release at the synapse …

Transmitter signalling is the universal chemical language of any nervous system, but little is
known about its early evolution. Here, we summarize data about the distribution and …

In November 1955, Geoffrey Harris published a paper based on the Christian A Herter
Lecture he had given earlier that year at Johns Hopkins University in Baltimore, MD, USA …

Abstract Neurons using serotonin (5-HT) as neurotransmitter and/or modulator have been
identified in the central nervous system in representatives from all vertebrate clades …

One reason that many central nervous system injuries, including those arising from traumatic
brain injury, spinal cord injury, and stroke, have limited recovery of function is that neurons …

Extensive neuropathological studies have established a compelling link between
abnormalities in structure and function of subcortical monoaminergic (MA-ergic) systems …

Dopamine plays an important role in fear and anxiety modulating a cortical brake that the
medial prefrontal cortex exerts on the anxiogenic output of the amygdala and have an …

The proposal on the existence of two main modes of intercellular communication in the
central nervous system (CNS) was introduced in 1986 and called wiring transmission (WT) …

Adult hippocampal neurogenesis is considered important for cognition. The integration of
newborn dentate gyrus granule cells into the existing network is regulated by afferent …