Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Fluid therapy is an integral component of perioperative management. In light of emerging
evidence in this area, the Perioperative Quality Initiative (POQI) convened an international …

Acute brain injury (ABI) covers various clinical entities that may require invasive mechanical
ventilation (MV) in the intensive care unit (ICU). The goal of MV, which is to protect the lung …

In the past 20 years since The Lancet Neurology was launched, the number of publications
about traumatic brain injury has steadily increased. The first paper published in the journal …

Importance The optimal timing for fixation of extremity fractures after traumatic brain injury
(TBI) remains controversial. Objective To investigate whether patients who underwent …

Background The optimal hemodynamic targets and management of patients with acute brain
injury are not completely elucidated, but recent evidence points to important impact on …

This study aimed to evaluate the effect of two restrictive cumulative fluid balance (CFB)
trends on survival and on major clinical outcomes in invasively ventilated patients with …

Timely diagnosis and management of pediatric acute liver failure (PALF) is of paramount
importance to improve survival. The Indian Society of Pediatric Gastroenterology …

Background The use of the passive leg raising (PLR) is limited in acute brain injury (ABI)
patients with increased intracranial pressure (ICP) since the postural change of the head …