Since the last few decades, the development of smart hydrogels, which can respond to
stimuli and adapt their responses based on external cues from their environments, has …

Bone degeneration associated with various diseases is increasing due to rapid aging,
sedentary lifestyles, and unhealthy diets. Living bone tissue has bioelectric properties critical …

Vitamin D (VD) is essential for bone homeostasis, but it is also involved in pleiotropic effects
on various organs and tissues. In adults, VD deficiency can cause or exacerbate …

Abstract More than 2.1 million age-related fractures occur in the United States annually,
resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of …

Background Patients with diabetes have an increased risk of nonunion and delayed union of
fractures. Macrophages have been shown as a key player in diabetic complications …

The number of diabetic patients has risen dramatically in recent decades, owing mostly to
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …

Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by
structural and functional abnormalities within the intricate network of microvessels beyond …

The repair of bone defects in patients with diabetes mellitus (DM) is a challenge in clinical
treatment mainly because of inhibited osteogenesis caused by stem cell dysfunction. Our …

Diabetes is constantly increasing at a rate that outpaces genetic variation and approaches to
pandemic magnitude. Skin cells physiology and the cutaneous healing response are …

Context The risk of fragility fractures is increased in both type 1 and type 2 diabetes.
Numerous biochemical markers reflecting bone and/or glucose metabolism have been …