Infections lacking precise diagnosis are often caused by a rare or uncharacterized
pathogen, a combination of pathogens, or a known pathogen carrying undocumented or …

Background Metagenomic next-generation sequencing (mNGS) has enabled the rapid,
unbiased detection and identification of microbes without pathogen-specific reagents …

The landscape of infectious fungal agents includes previously unidentified or rare
pathogens with the potential to cause unprecedented casualties in biodiversity, food …

Metagenomic next-generation sequencing is a novel diagnostic test with the potential to
revolutionize the diagnosis of pediatric meningitis and encephalitis through unbiased …

Meningoencephalitis of unknown origin (MUO) describes a group of meningoencephalitides
in dogs with a hitherto unknown trigger. An infectious agent has been suggested as one …

Simple Summary Significant progress in next-generation sequencing (NGS) is positioning
this technology as a key tool to be utilized in clinical diagnosis of disease agents and/or for …

Aim The aim of the present study is to compare the performance of 16S rRNA Nanopore
sequencing and conventional culture in detecting infectious pathogens in patients with …

The clinical presentation of tick-borne encephalitis virus (TBEV) infection varies from
asymptomatic to severe meningoencephalitis or meningoencephalomyelitis. The TBEV …

Simple Summary With advances in NGS technology, the high ratio of throughput/cost per
base has allowed research laboratories to develop diagnostic protocols that can detect …

Background: Central nervous system (CNS) infection is associated with high rates of
morbidity and mortality, and despite advancements in molecular testing, aseptic meningitis …