The evolution of cancer surgery and future perspectives

L Wyld, RA Audisio, GJ Poston - Nature reviews Clinical oncology, 2015 - nature.com
Surgery is the oldest oncological discipline, dating back thousands of years. Prior to the
advent of anaesthesia and antisepsis 150 years ago, only the brave, desperate, or ill …

Diagnostic accuracy of MRI for assessment of T category, lymph node metastases, and circumferential resection margin involvement in patients with rectal cancer: a …

E Al-Sukhni, L Milot, M Fruitman, J Beyene… - Annals of surgical …, 2012 - Springer
Background Magnetic resonance imaging (MRI) is increasingly being used for rectal cancer
staging. The purpose of this study was to determine the accuracy of phased array MRI for T …

Modified FOLFOX6 with or without radiation versus fluorouracil and leucovorin with radiation in neoadjuvant treatment of locally advanced rectal cancer: initial results …

Y Deng, P Chi, P Lan, L Wang, W Chen… - Journal of clinical …, 2016 - ascopubs.org
Purpose Total mesorectal excision with fluorouracil-based preoperative chemoradiotherapy
and postoperative chemotherapy is a standard treatment of locally advanced rectal cancer …

Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer

E Kapiteijn, CAM Marijnen, ID Nagtegaal… - … England Journal of …, 2001 - Mass Medical Soc
Background Short-term preoperative radiotherapy and total mesorectal excision have each
been shown to improve local control of disease in patients with resectable rectal cancer. We …

Neutrophil‐lymphocyte ratio as a prognostic factor in colorectal cancer

SR Walsh, EJ Cook, F Goulder… - Journal of surgical …, 2005 - Wiley Online Library
Abstract Background and Objectives Simple methods to identify colorectal cancer patients at
risk of recurrence are needed. This study aimed to determine if neutrophil‐to‐lymphocyte …

Understanding optimal colonic cancer surgery: comparison of Japanese D3 resection and European complete mesocolic excision with central vascular ligation

NP West, H Kobayashi, K Takahashi… - Journal of clinical …, 2012 - ascopubs.org
Purpose Over recent years, patient outcomes after colon cancer resection have not
improved to the same degree as for rectal cancer. Japanese D3 resection and European …

Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by …

A Dewdney, D Cunningham, J Tabernero… - Journal of Clinical …, 2012 - ascopubs.org
Purpose To evaluate the addition of cetuximab to neoadjuvant chemotherapy before
chemoradiotherapy in high-risk rectal cancer. Patients and Methods Patients with operable …

Accuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery

RGH Beets-Tan, GL Beets, RFA Vliegen, AGH Kessels… - The Lancet, 2001 - thelancet.com
Background Incomplete surgical removal of the circumferential tumour spread is believed to
be the main cause of local recurrence after resection of rectal cancer. This study assessed …

Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter …

CAM Marijnen, E Kapiteijn… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: Total mesorectal excision (TME) surgery in the treatment of rectal cancer has
been shown to result in a reduction in the number of local recurrences in retrospective …

Impact of number of nodes retrieved on outcome in patients with rectal cancer

JE Tepper, MJ O'connell, D Niedzwiecki… - Journal of clinical …, 2001 - ascopubs.org
PURPOSE: We postulated that the pathologic evaluation of the lymph nodes of surgical
specimens from patients with rectal cancer can have a substantial impact on time to relapse …