Multiaperture sample positioning and analysis system

H Vogel, C Schmidt - US Patent 7,244,349, 2007 - Google Patents
US7244349B2 - Multiaperture sample positioning and analysis system - Google Patents
US7244349B2 - Multiaperture sample positioning and analysis system - Google Patents …

Electrical field stimulation of eukaryotic cells

PR Augustine, RM Bugianesi, GS Kath… - US Patent …, 2007 - Google Patents
2007-05-30 Assigned to MERCK & CO., INC. reassignment MERCK & CO., INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Multiaperture sample positioning and analysis system

H Vogel, C Schmidt - US Patent 7,201,836, 2007 - Google Patents
US7201836B2 - Multiaperture sample positioning and analysis system - Google Patents
US7201836B2 - Multiaperture sample positioning and analysis system - Google Patents …

Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (RTCA) cardio instruments

N Li, X Wang, YA Abassi, B **, WF Zhang… - US Patent …, 2017 - Google Patents
(57) ABSTRACT A method of determining one or more beating parameters for use in
cardiomyocyte beating analysis including: providing a cell analysis device including wells …

Sample positioning and analysis system

H Vogel, C Schmidt - US Patent 7,387,715, 2008 - Google Patents
US 2003/O146091 A1 Aug. 7, 2003 Related US Application Data Continuation-in-part of
application No. 10/229,863, filed on Aug. 27, 2002, now Pat. No. 7,244,349, which is a …

Real-time electronic cell sensing system and applications for cytotoxicity profiling and compound assays

YA Abassi, X Wang, X Xu - US Patent 9,399,787, 2016 - Google Patents
(57) ABSTRACT A method of performing an assay of a response of two or more cell types to
a test compound, including: providing a device for monitoring cell-substrate impedance …

Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers

H Vogel, C Schmidt - US Patent 6,758,961, 2004 - Google Patents
US. PATENT DOCUMENTS 2002/0182627 A1 12/2002 Wang et a1. _ 2002/0190732 A1
12/2002 Cheng etal. 5,169,600 A 12/1992 lshllaka eta1~ 2003/0059936 A1 3/2003 …

Nanostructured separation and analysis devices for biological membranes

GP Lopez, SRJ Brueck, LK Ista - US Patent App. 11/825,298, 2011 - Google Patents
The present invention provides a nanostructured device comprising a Substrate including
nanotroughs therein; and a lipid bilayer Suspended on or Supported in the Substrate. A …

Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways

YA Abassi, L Zhao, N Ke, X Wang, X Xu - US Patent 10,215,748, 2019 - Google Patents
Use of impedance devices in methods of generating a time dependent cellular profiles
(TCRP) for the modulation of oncogene addicted cells and comparing the impedance based …

Dynamic monitoring of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) activity and pathways in living cells using real-time microelectronic cell …

YA Abassi, N Yu, J Atienza, X Xu, X Wang - US Patent 10,067,121, 2018 - Google Patents
Use of cell-substrate impedance based methods for screening for agonists of G-Protein
Coupled Receptors (GPCRs) or inhibitors of a Receptor Tyrosine Kinases (RTKs) …