Host genetics and microbiota interactions in colorectal cancer: shared or independent risk?

I Romero-Garmendia, K Garcia-Etxebarria - Microorganisms, 2022 - mdpi.com
The role of microbiota in colorectal cancer has been studied since alterations in its
composition were observed. In addition, there are more and more pieces of evidence that …

From Omic Layers to Personalized Medicine in Colorectal Cancer: The Road Ahead

I Romero-Garmendia, K Garcia-Etxebarria - Genes, 2023 - mdpi.com
Colorectal cancer is a major health concern since it is a highly diagnosed cancer and the
second cause of death among cancers. Thus, the most suitable biomarkers for its diagnosis …

Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments

K Garcia-Etxebarria, A Etxart, M Barrero, B Nafria… - Cancers, 2023 - mdpi.com
Simple Summary Some colorectal cancer (CRC) outcomes are partially associated with
genetics, and different studies have proposed several genetic variants as predictors …

System genetic analysis of intestinal cancer and periodontitis development as influenced by aging and diabesity using Collaborative Cross mice

IM Lone, O Zohud, K Midlej, C Brenner… - Animal Models and …, 2025 - Wiley Online Library
It is increasingly recognized that young, chow‐fed inbred mice poorly model the complexity
of human carcinogenesis. In humans, age and adiposity are major risk factors for …

Clinical, Pathological, and Molecular Characteristics in Colorectal Cancer

S Dedieu, O Bouché - Cancers, 2022 - mdpi.com
Carcinogenesis steps have commonly involved the growth and expansion of adenomatous
polyps from normal colorectal epithelium to adenoma through a multistep process of several …

Optimization of Multi-Ancestry Polygenic Risk Score Disease Prediction Models

J Lerga-Jaso, A Terpolovsky, B Novković, A Osama… - medRxiv, 2024 - medrxiv.org
Background Polygenic risk scores (PRS) have ushered in a new era in genetic
epidemiology, offering insights into individual predispositions to a wide range of diseases …

[ZITATION][C] Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments. Cancers 2023, 15, 4688

K Garcia-Etxebarria, A Etxart, M Barrero, B Nafria… - 2023