The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …

The immunopathogenesis of psoriasis, a common chronic inflammatory disease of the skin,
is incompletely understood. Here we demonstrate, using a combination of single cell and …

Th subsets are defined according to their production of lineage-indicating cytokines and
functions. In this study, we have identified a subset of human Th cells that infiltrates the …

Psoriasis is a chronic, immune‐mediated skin condition with a high rate of psychiatric
comorbidity, which often goes unrecognized. Beyond the negative consequences of mood …

Background Cutaneous pigmentation is regulated by a complex melanogenic network in
which both keratinocytes and fibroblasts synthesize growth factors and cytokines. Solar …

Please cite this paper as: The role of keratinocyte growth factor in melanogenesis: a
possible mechanism for the initiation of solar lentigines. Experimental Dermatology 2010; …

Fibroblasts are crucial components of the skin structure. They were traditionally believed to
maintain the skin's structure by producing extracellular matrix and other elements. Recent …

KGF (Keratinocyte Growth Factor), also known as FGF7, is a potent mitogen for different
types of epithelial cells, which regulates migration and differentiation of these cells and …

Background Data indicate that in psoriasis, abnormalities are already present in nonlesional
skin. Transforming growth factor‐β and keratinocyte growth factor (KGF), together with …

Palifermin (Kepivance™) is the first therapeutic approved by the Food and Drug
Administration for preventing and managing the oral mucositis provoked by myelotoxic and …