Diagnosis of Lyme borreliosis

ME Aguero-Rosenfeld, G Wang… - Clinical microbiology …, 2005 - Am Soc Microbiol
SUMMARY A large amount of knowledge has been acquired since the original descriptions
of Lyme borreliosis (LB) and of its causative agent, Borrelia burgdorferi sensu stricto. The …

Molecular Ty** of Borrelia burgdorferiSensu Lato: Taxonomic, Epidemiological, and Clinical Implications

G Wang, AP Van Dam, I Schwartz… - Clinical microbiology …, 1999 - Am Soc Microbiol
Borrelia burgdorferi sensu lato, the spirochete that causes human Lyme borreliosis (LB), is a
genetically and phenotypically divergent species. In the past several years, various …

A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi

S Casjens, N Palmer, R Van Vugt… - Molecular …, 2000 - Wiley Online Library
We have determined that Borrelia burgdorferi strain B31 MI carries 21 extrachromosomal
DNA elements, the largest number known for any bacterium. Among these are 12 linear and …

Lyme borreliosis in europe and north america

J Piesman, L Gern - Parasitology, 2004 - cambridge.org
Since the discovery of the Lyme disease spirochete in North America in 1982 and in Europe
in 1983, a plethora of studies on this unique group of spirochetes that comprise Borrelia …

Sequence ty** reveals extensive strain diversity of the Lyme borreliosis agents Borrelia burgdorferi in North America and Borrelia afzelii in Europe

J Bunikis, U Garpmo, J Tsao, J Berglund… - …, 2004 - microbiologyresearch.org
The genetic polymorphism of Borrelia burgdorferi and Borrelia afzelii, two species that cause
Lyme borreliosis, was estimated by sequence ty** of four loci: the rrs–rrlA intergenic …

Lyme disease: a rigorous review of diagnostic criteria and treatment

AT Borchers, CL Keen, AC Huntley… - Journal of autoimmunity, 2015 - Elsevier
Lyme disease was originally identified in Lyme, Connecticut, based upon an unusual cluster
of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently …

Genetics of Borrelia burgdorferi

D Brisson, D Drecktrah, CH Eggers… - Annual review of …, 2012 - annualreviews.org
The spirochetes in the Borrelia burgdorferi sensu lato genospecies group cycle in nature
between tick vectors and vertebrate hosts. The current assemblage of B. burgdorferi sensu …

Nervous system Lyme disease

JJ Halperin - Current infectious disease reports, 2015 - Springer
Lyme disease, a multisystem spirochetal infection, continues to be the subject of
considerable debate, but not controversy. Recent years have seen improvements in …

PCR in laboratory diagnosis of human Borrelia burgdorferi infections

BL Schmidt - Clinical microbiology reviews, 1997 - Am Soc Microbiol
The laboratory diagnosis of Lyme borreliosis, the most prevalent vector-borne disease in the
United States and endemic in parts of Europe and Asia, is currently based on serology with …

Trends in surveillance data of human Lyme borreliosis from six federal states in eastern Germany, 2009–2012

H Wilking, K Stark - Ticks and tick-borne diseases, 2014 - Elsevier
Lyme borreliosis (LB) is the most frequent vector-borne disease in Germany. For more than
10 years, data from mandatory notifications have been available from 6 federal states in the …