[HTML][HTML] An update on current pharmacotherapeutic options for the treatment of ulcerative colitis

F Ferretti, R Cannatelli, MC Monico, G Maconi… - Journal of Clinical …, 2022 - mdpi.com
The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

The role of early biologic therapy in inflammatory bowel disease

DR Berg, JF Colombel, R Ungaro - Inflammatory bowel diseases, 2019 - academic.oup.com
The goals for treatment of inflammatory bowel diseases (IBDs) are changing from
elimination of symptoms toward complete disease control—a process that demands both …

ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 2: IBD scores and general principles and technical aspects

A Sturm, C Maaser, E Calabrese… - Journal of Crohn's …, 2019 - academic.oup.com
There are several scoring systems presently available to classify disease severity in
ulcerative colitis [UC] within the multiple domains of disease activity, which aid objective …

ECCO position paper: harmonization of the approach to ulcerative colitis histopathology

F Magro, G Doherty, L Peyrin-Biroulet… - Journal of Crohn's …, 2020 - academic.oup.com
Currently, the main targets of drug therapy for ulcerative colitis [UC] are endoscopic and
clinical remission. However, there is active discussion about the additional advantages of …

European evidence based consensus for endoscopy in inflammatory bowel disease

V Annese, M Daperno, MD Rutter… - Journal of Crohn's …, 2013 - academic.oup.com
Endoscopy plays an essential role in the diagnosis, management, prognosis, and
surveillance of inflammatory bowel disease (IBD), but surprisingly there are few available …

Beyond endoscopic mucosal healing in UC: histological remission better predicts corticosteroid use and hospitalisation over 6 years of follow-up

RV Bryant, DC Burger, J Delo, AJ Walsh, S Thomas… - Gut, 2016 - gut.bmj.com
Background Endoscopic mucosal healing is an established treatment target for UC, yet the
value of achieving histological remission remains unclear. Aims To evaluate histological …

Systematic review: histological remission in inflammatory bowel disease. Is 'complete'remission the new treatment paradigm? An IOIBD initiative

RV Bryant, S Winer, T SPL… - Journal of Crohn's and …, 2014 - academic.oup.com
Background and aims: Advances in the medical management of inflammatory bowel
disease (IBD) have altered treatment targets. Endoscopic mucosal healing is associated …

Histologic normalization occurs in ulcerative colitis and is associated with improved clinical outcomes

B Christensen, SB Hanauer, J Erlich, O Kassim… - Clinical …, 2017 - Elsevier
Background & Aims Mucosal healing, determined by histologic analysis, is a potential
therapeutic target for patients with ulcerative colitis (UC). However, the histologic features of …

[HTML][HTML] Histologic remission: the ultimate therapeutic goal in ulcerative colitis?

L Peyrin–Biroulet, A Bressenot, W Kampman - Clinical Gastroenterology …, 2014 - Elsevier
Ulcerative colitis (UC) is a disease of the mucosal layer, and activity of the disease is
assumed to be related to mucosal appearance. Mucosal healing has emerged as a major …

Histology grade is independently associated with relapse risk in patients with ulcerative colitis in clinical remission: a prospective study

T Zenlea, EU Yee, L Rosenberg, M Boyle… - Official journal of the …, 2016 - journals.lww.com
OBJECTIVES: Objective evidence of inflammation has been associated with the risk of
relapse in patients with ulcerative colitis (UC) who are in clinical remission. We compared …