Negative symptoms in schizophrenia: a review and clinical guide for recognition, assessment, and treatment

CU Correll, NR Schooler - Neuropsychiatric disease and treatment, 2020 - Taylor & Francis
Schizophrenia is frequently a chronic and disabling disorder, characterized by
heterogeneous positive and negative symptom constellations. The objective of this review …

Neuroscience of apathy and anhedonia: a transdiagnostic approach

M Husain, JP Roiser - Nature Reviews Neuroscience, 2018 - nature.com
Apathy and anhedonia are common syndromes of motivation that are associated with a wide
range of brain disorders and have no established therapies. Research using animal models …

Negative symptoms of schizophrenia: new developments and unanswered research questions

S Galderisi, A Mucci, RW Buchanan… - The Lancet Psychiatry, 2018 - thelancet.com
Negative symptoms of schizophrenia are associated with poor functional outcome and place
a substantial burden on people with this disorder, their families, and health-care systems …

The current conceptualization of negative symptoms in schizophrenia

SR Marder, S Galderisi - World Psychiatry, 2017 - Wiley Online Library
Negative symptoms have long been conceptualized as a core aspect of schizophrenia. They
play a key role in the functional outcome of the disorder, and their management represents a …

[HTML][HTML] The anatomy of apathy: a neurocognitive framework for amotivated behaviour

C Le Heron, MAJ Apps, M Husain - Neuropsychologia, 2018 - Elsevier
Apathy is a debilitating syndrome associated with many neurological disorders, including
several common neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

The relationship between negative symptoms and depression in schizophrenia: a systematic review

CR Krynicki, R Upthegrove, JFW Deakin… - Acta Psychiatrica …, 2018 - Wiley Online Library
Objective To provide an update on the evidence base for the nature of the relationship
between negative symptoms and depressive features in people with schizophrenia, and …

Immediate and sustained outcomes and moderators associated with metacognitive training for psychosis: a systematic review and meta-analysis

D Penney, G Sauve, D Mendelson… - JAMA …, 2022 - jamanetwork.com
Importance A substantial increase in the number of trials examining metacognitive training
(MCT) for psychosis necessitates an updated examination of the outcomes associated with …

A transdiagnostic review of negative symptom phenomenology and etiology

GP Strauss, AS Cohen - Schizophrenia bulletin, 2017 - academic.oup.com
In the DSM5, negative symptoms are 1 of the 5 core dimensions of psychopathology
evaluated for schizophrenia. However, negative symptoms are not pathognomonic—they …

Treating negative symptoms in schizophrenia: an update

G Remington, G Foussias, G Fervaha, O Agid… - … treatment options in …, 2016 - Springer
Opinion Statement Interest in the negative symptoms of schizophrenia has increased rapidly
over the last several decades, paralleling a growing interest in functional, in addition to …