Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …
Endothelial progenitor cells and integrins: adhesive needs
In the last decade there have been multiple studies concerning the contribution of
endothelial progenitor cells (EPCs) to new vessel formation in different physiological and …
endothelial progenitor cells (EPCs) to new vessel formation in different physiological and …
Shear stress: An essential driver of endothelial progenitor cells
The blood flow through vessels produces a tangential, or shear, stress sensed by their
innermost layer (ie, endothelium) and representing a major hemodynamic force. In humans …
innermost layer (ie, endothelium) and representing a major hemodynamic force. In humans …
Capture of endothelial cells under flow using immobilized vascular endothelial growth factor
We demonstrate the ability of immobilized vascular endothelial growth factor (VEGF) to
capture endothelial cells (EC) with high specificity under fluid flow. To this end, we …
capture endothelial cells (EC) with high specificity under fluid flow. To this end, we …
Enhancing Mesenchymal Stromal Cell Potency: Inflammatory Licensing via Mechanotransduction
Mesenchymal stromal cells (MSC) undergo functional maturation upon their migration from
bone marrow and introduction to a site of injury. This inflammatory licensing leads to …
bone marrow and introduction to a site of injury. This inflammatory licensing leads to …
Parallel-plate flow chamber and continuous flow circuit to evaluate endothelial progenitor cells under laminar flow shear stress
WO Lane, AE Jantzen, TA Carlon… - Journal of …, 2012 - pmc.ncbi.nlm.nih.gov
The overall goal of this method is to describe a technique to subject adherent cells to
laminar flow conditions and evaluate their response to well quantifiable fluid shear …
laminar flow conditions and evaluate their response to well quantifiable fluid shear …
Impact of REDV peptide density and its linker structure on the capture, movement, and adhesion of flowing endothelial progenitor cells in microfluidic devices
A Mahara, K Kitagawa, A Otaka, T Nakaoki… - Materials Science and …, 2021 - Elsevier
Ligand-immobilization to stents and vascular grafts is expected to promote
endothelialization by capturing flowing endothelial progenitor cells (EPCs). However, the …
endothelialization by capturing flowing endothelial progenitor cells (EPCs). However, the …
Endothelial colony forming cell rolling and adhesion supported by peptide-grafted hydrogels
The aim of this study was to investigate the ability of peptides and peptide combinations to
support circulating endothelial colony forming cell (ECFC) rolling and adhesion under shear …
support circulating endothelial colony forming cell (ECFC) rolling and adhesion under shear …
Peptide-grafted poly (ethylene glycol) hydrogels support dynamic adhesion of endothelial progenitor cells
This study investigated the dynamic adhesion of endothelial progenitor cells (EPCs) to
peptide-grafted poly (ethylene glycol) diacrylate (PEGDA) hydrogels and determined the …
peptide-grafted poly (ethylene glycol) diacrylate (PEGDA) hydrogels and determined the …
Effect of cyclic uniaxial mechanical strain on endothelial progenitor cell differentiation
Abstract Purpose Endothelial progenitor cells (EPCs) have been used as an autologous or
allogeneic source in multiple tissue engineering applications. EPCs possess high …
allogeneic source in multiple tissue engineering applications. EPCs possess high …