Therapeutic approaches for cardiac regeneration and repair
Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar …
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar …
Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics
Current therapies for heart failure after myocardial infarction are limited and non-curative.
Although regenerative approaches are receiving significant attention, clinical efforts that …
Although regenerative approaches are receiving significant attention, clinical efforts that …
Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases
Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …
Growth factor delivery: Defining the next generation platforms for tissue engineering
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …
allowing the formation of tissues. Understanding the key requirements for growth factor …
Nanomedicine and drug delivery systems in cancer and regenerative medicine
Nanomedicine and drug delivery technologies play a prominent role in modern medicine,
facilitating better treatments than conventional drugs. Nanomedicine is being increasingly …
facilitating better treatments than conventional drugs. Nanomedicine is being increasingly …
The multifunctional contribution of FGF signaling to cardiac development, homeostasis, disease and repair
The current focus on cardiovascular research reflects society's concerns regarding the
alarming incidence of cardiac-related diseases and mortality in the industrialized world and …
alarming incidence of cardiac-related diseases and mortality in the industrialized world and …
Hydrogel based approaches for cardiac tissue engineering
Heart failure still represents the leading cause of death worldwide. Novel strategies using
stem cells and growth factors have been investigated for effective cardiac tissue …
stem cells and growth factors have been investigated for effective cardiac tissue …
Stimulating cardiogenesis as a treatment for heart failure
TR Heallen, ZA Kadow, JH Kim, J Wang… - Circulation …, 2019 - Am Heart Assoc
After myocardial injury, cardiomyocyte loss cannot be corrected by using currently available
clinical treatments. In recent years, considerable effort has been made to develop cell-based …
clinical treatments. In recent years, considerable effort has been made to develop cell-based …
[HTML][HTML] Cardiac tissue engineering for myocardial infarction treatment
Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …
Toward regeneration of the heart: bioengineering strategies for immunomodulation
Myocardial Infarction (MI) is the most common cardiovascular disease. An average-sized MI
causes the loss of up to 1 billion cardiomyocytes and the adult heart lacks the capacity to …
causes the loss of up to 1 billion cardiomyocytes and the adult heart lacks the capacity to …