Precision Medicine for Cardiovascular Prevention and Population Health: A Bridge Too Far?

FR Giugni, JD Berry, A Khera, AM Shah, JA de Lemos - Circulation, 2024 - ahajournals.org
Precision medicine aims to provide personalized clinical care guided by tools that reflect
underlying pathophysiology. The need for such an approach has never been greater in …

Cardiac arrhythmia in individuals with steroid sulfatase deficiency (X-linked ichthyosis): candidate anatomical and biochemical pathways

GH Wren, W Davies - Essays in Biochemistry, 2024 - portlandpress.com
Circulating steroids, including sex hormones, can affect cardiac development and function.
In mammals, steroid sulfatase (STS) is the enzyme solely responsible for cleaving sulfate …

X-Chromosome–Linked miRNAs Regulate Sex Differences in Cardiac Physiology

JI Emerson, W Shi, J Paredes-Larios… - Circulation …, 2025 - ahajournals.org
BACKGROUND: Males and females exhibit distinct anatomic and functional characteristics
of the heart, predisposing them to specific disease states. METHODS: We identified …

Personalized clinical management of patients with atrial fibrillation: is a biomarker-based strategy for prediction of sinus rhythm persistence ready for prime time?

G Boriani, DA Mei, JF Imberti - European Heart Journal, 2024 - academic.oup.com
Personalized clinical management of patients with atrial fibrillation: is a biomarker-based
strategy for prediction of sinus rhy Page 1 https://doi.org/10.1093/eurheartj/ehae720 EDITORIAL …

Atrial proteomic profiling reveals a switch towards profibrotic gene expression program in CREM-IbΔC-X mice with persistent atrial fibrillation

S Zhao, MM Hulsurkar, SK Lahiri… - Journal of Molecular and …, 2024 - Elsevier
Background Overexpression of the CREM (cAMP response element-binding modulator)
isoform CREM-IbΔC-X in transgenic mice (CREM-Tg) causes the age-dependent …

What the blood knows: predicting atrial fibrillation risk in hypertrophic cardiomyopathy patients

G Jabbour, R Tadros, CA Remme - Europace, 2024 - academic.oup.com
What the blood knows: predicting atrial fibrillation risk in hypertrophic cardiomyopathy patients
| EP Europace | Oxford Academic Skip to Main Content Advertisement intended for healthcare …

Proteomics and recurrence of atrial fibrillation: a pilot study nested in the PREDIMAR trial

C Razquin, J Fernandez-Irigoyen, MT Barrio-López… - Lifestyle …, 2023 - karger.com
Introduction: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia
worldwide. Although catheter ablation is the most efficacious therapy, relapses occur …

Single-cell Transcriptomic Atlas of Human Atrial Fibrillation

Q Wang, X He, D Wang, WD Gao - 2024 - researchsquare.com
Atrial fibrillation (AF) is becoming a significant public health challenge, presenting moderate
treatment effects and a high recurrence rate. The lack of a complete, in-depth understanding …

Exploring the psychological and physiological issues associated with X-linked ichthyosis

G Wren - 2024 - orca.cardiff.ac.uk
This thesis investigates the psychological and physiological issues associated with
congenital skin conditions, with a particular focus on X-linked ichthyosis (XLI), a rare …

[HTML][HTML] Вариабельность генов натрийуретических пептидов у пациентов с ревматической болезнью сердца и фибрилляцией предсердий

АВ Синицкая, МВ Хуторная, ОН Хрячкова… - Патология …, 2024 - cyberleninka.ru
Актуальность. Одна из самых распространенных аритмий у пациентов с
ревматической болезнью сердца—фибрилляция предсердий. Патофизиологические …