Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global
health. Correlating with liver disease progression, fibrosis is a key factor for liver disease …

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Hepatitis C virus (HCV) infection is a major source of morbidity and mortality in the United
States. HCV is transmitted primarily through parenteral exposures to infectious blood or …

Abstract The Virus Variation Resource is a value-added viral sequence data resource
hosted by the National Center for Biotechnology Information. The resource is located at …

Hepatitis C (HCV) is a major cause of liver disease, in which a third of individuals with
chronic HCV infections may develop liver cirrhosis. In a chronic HCV infection, host immune …

The central paradigm of vaccination is to generate resistance to infection by a specific
pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two …

Hepatitis C virus (HCV) infection is a major cause of severe liver disease including chronic
hepatitis, cirrhosis and hepatocellular carcinoma. The HCV burden in public health is …

Hepatitis C virus (HCV) is a significant cause of hepatocellular carcinoma (HCC). The direct-
acting antivirals marked a new era of HCV therapy and are associated with greater than …

Chronic infection with the hepatitis C virus (HCV) remains a major health problem affecting
approximately 58 million people worldwide. In the era of interferon (IFN)-based regimens …

Microbial diseases have become quite common in recent years. The interest in new
antimicrobial drugs is increasing due to the possible side effects of synthetic drugs and the …