The pineal hormone melatonin has attracted great scientific interest since its discovery in
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …

Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

The endoplasmic reticulum (ER) is crucial for protein quality control, and disruptions in its
function can lead to various diseases. ER stress triggers an adaptive response called the …

Melatonin is a neurohormone synthesized from dietary tryptophan in various organs,
including the pineal gland and the retina. In the pineal gland, melatonin is produced at night …

The indolamine hormone melatonin, also known as N-acetyl-5-methoxytrypamine, is
frequently associated with circadian rhythm regulation. Light can suppress melatonin …

Melatonin, a multifunctional molecule that is present in all living organisms studied, is
synthesized in plant cells in several intercellular organelles including in the chloroplasts and …

Objective To systematically summarise and evaluate the existing evidence on the effect of
diet on the management of type 2 diabetes and prevention of complications. Design …

Metabolic syndrome has been associated in many studies with working in shifts. Even if the
mechanistic details are not fully understood, forced sleep deprivation and exposure to light …

Background Use of melatonin supplements has been increasing substantially in both
children and adults in the USA; however, their long-term cardiometabolic effects remain …