Neuroblastoma and MYCN

M Huang, WA Weiss - Cold Spring …, 2013‏ - perspectivesinmedicine.cshlp.org
Neuroblastoma, the most common extracranial solid tumor of childhood, is thought to
originate from undifferentiated neural crest cells. Amplification of the MYC family member …

The chick embryo chorioallantoic membrane as a model for tumor biology

D Ribatti - Experimental cell research, 2014‏ - Elsevier
Among the in vivo models, the chick embryo chorioallantoic membrane (CAM) has been
used to implant several tumor types as well as malignant cell lines to study their growth rate …

Chick embryo chorioallantoic membrane as a useful tool to study angiogenesis

D Ribatti - International review of cell and molecular biology, 2008‏ - Elsevier
The chick embryo chorioallantoic membrane (CAM) is an extraembryonic membrane
mediating gas and nutrient exchanges until hatching. Since it has a dense capillary network …

The CAM assay as an alternative in vivo model for drug testing

R Schneider-Stock, D Ribatti - Organotypic Models in Drug Development, 2021‏ - Springer
In the last decade, the chicken chorioallantoic membrane (CAM) assay has been re-
discovered in cancer research to study the molecular mechanisms of anti-cancer drug …

Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical …

P Bocca, E Di Carlo, I Caruana, L Emionite… - …, 2018‏ - Taylor & Francis
ABSTRACT GD2-redirected chimeric antigen receptor (CAR) T lymphocytes represent a
promising therapeutic option for immunotherapy of neuroblastoma (NB). However, despite …

[کتاب][B] Pediatric Urology E-Book: Expert Consult-Online and Print

JG Gearhart, RC Rink, PDE Mouriquand - 2009‏ - books.google.com
Pediatric Urology is an up-to-date, clinical reference that provides detailed descriptions of
the best approaches for the functional, biological, and morphological aspects of the urinary …

Tumor origin of endothelial cells in human neuroblastoma

A Pezzolo, F Parodi, MV Corrias, R Cinti… - Journal of Clinical …, 2007‏ - ascopubs.org
Purpose Malignant cells are genetically unstable and prone to develop chemotherapy
resistance, whereas tumor vasculature is usually of host origin and genetically stable. Tumor …

[PDF][PDF] The chick embryo chorioallantoic membrane in the study of tumor angiogenesis

D Ribatti - Rom J Morphol Embryol, 2008‏ - rjme.ro
The chick embryo chorioallantoic membrane (CAM) is commonly used as an experimental in
vivo assay to study both angiogenesis and antiangiogenesis in response to tissues, cells or …

N-myc is a novel regulator of PI3K-mediated VEGF expression in neuroblastoma

J Kang, PG Rychahou, TA Ishola, JM Mourot, BM Evers… - Oncogene, 2008‏ - nature.com
Angiogenesis in neuroblastoma (NB) correlates with increased expression of vascular
endothelial growth factor (VEGF) and a worse clinical outcome. Other cellular markers, such …

The chorioallantoic membrane as a bio-barrier model for the evaluation of nanoscale drug delivery systems for tumour therapy

E Preis, J Schulze, B Gutberlet, SR Pinnapireddy… - Advanced drug delivery …, 2021‏ - Elsevier
Abstract In 2010, the European Parliament and the European Union adopted a directive on
the protection of animals used for scientific purposes. The directive aims to protect animals …