Macrophage polarization and metabolism in atherosclerosis

P Hou, J Fang, Z Liu, Y Shi, M Agostini… - Cell Death & …, 2023 - nature.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

[HTML][HTML] The impact of toxic metal bioaccumulation on colorectal cancer: Unravelling the unexplored connection

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of the Total …, 2024 - Elsevier
Colorectal cancer is a major public health concern, with increasing incidence and mortality
rates worldwide. Environmental factors, including exposure to toxic metals, such as lead …

[HTML][HTML] Aluminium bioaccumulation in colon cancer, im**ing on epithelial-mesenchymal-transition and cell death

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of The Total …, 2024 - Elsevier
We investigated the presence of aluminium (Al) in human colon cancer samples and its
potential association with biological processes involved in cancer progression, such as …

Inflammation in coronary artery disease-clinical implications of novel HDL-cholesterol–related inflammatory parameters as predictors

X Guo, L Ma - Coronary Artery Disease, 2023 - journals.lww.com
Coronary artery disease (CAD) is the leading cause of death worldwide. Inflammation and
atherosclerotic plaques are the primary pathological mechanisms of CAD. Upon stimulation …

Two-faced Janus: the dual role of macrophages in atherosclerotic calcification

OJ Waring, NT Skenteris, EAL Biessen… - Cardiovascular …, 2022 - academic.oup.com
Calcification is an independent predictor of atherosclerosis-related cardiovascular events.
Microcalcification is linked to inflamed, unstable lesions, in comparison to the fibrotic stable …

Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular …

L István, C Czakó, Á Élő, Z Mihály, P Sótonyi, A Varga… - Geroscience, 2021 - Springer
Carotid artery stenosis (CAS) is a consequence of systemic atherosclerotic disease affecting
the aging populations of the Western world. CAS is frequently associated with cognitive …

Inflammation and microcalcification: a never-ending vicious cycle in atherosclerosis?

L Kawtharany, L Bessueille, H Issa… - Journal of Vascular …, 2022 - karger.com
Inflammatory cells and cytokines are known for long to worsen the development of
atherosclerotic plaques in mice, and intense efforts are today devoted to develop anti …

Macrophage polarization in the perivascular fat was associated with coronary atherosclerosis

DS Farias‐Itao, CA Pasqualucci… - Journal of the …, 2022 - Am Heart Assoc
Background Inflammation of the perivascular adipose tissue (PvAT) may be related to
atherosclerosis; however, the association of polarized macrophages in the pericoronary …

Atherosclerosis calcification: focus on lipoproteins

JG Neels, G Leftheriotis, G Chinetti - Metabolites, 2023 - mdpi.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of
lipids in the vessel wall, leading to the formation of an atheroma and eventually to the …

Impact of the environmental pollution on cardiovascular diseases: From epidemiological to molecular evidence

M Scimeca, V Palumbo, E Giacobbi, F Servadei… - Heliyon, 2024 - cell.com
Environmental pollution poses a significant threat to human health, particularly concerning
its impact on cardiovascular diseases (CVDs). This review synthesizes epidemiological and …