Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Over the years, click and bioorthogonal reactions have been the subject of considerable
research efforts. These high-performance chemical reactions have been developed to meet …

Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Targeting nanoparticle (NP) carriers to sites of disease is critical for their successful use as
drug delivery systems. Along with optimization of physicochemical properties, researchers …

Hyaluronic acid (HA) is a large non-sulphated glycosaminoglycan that is an important
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …

Traditional supplements of selenium generally have a low degree of absorption and
increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of …

Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Polymeric micelles (PMs) have been widely investigated as nanocarriers for drug delivery
and cancer treatments due to their excellent physicochemical properties, drug loading and …