Metabolic engineering advances and prospects for amino acid production

VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

Cyclic peptides as drugs for intracellular targets: the next frontier in peptide therapeutic development

LK Buckton, MN Rahimi… - Chemistry–A European …, 2021 - Wiley Online Library
Develo** macrocyclic peptides that can reach intracellular targets is a significant
challenge. This review discusses the most recent strategies used to develop cell permeable …

Recent advances in methylation: A guide for selecting methylation reagents

Y Chen - Chemistry–A European Journal, 2019 - Wiley Online Library
Methylation is a well‐known structural modification in organic and medicinal chemistry. This
review summarizes recent advances in methylation by categorizing specific methylation …

Exploring FDA-approved frontiers: Insights into natural and engineered peptide analogues in the GLP-1, GIP, GHRH, CCK, ACTH, and α-MSH realms

O Al Musaimi - Biomolecules, 2024 - mdpi.com
Peptides continue to gain significance in the pharmaceutical arena. Since the unveiling of
insulin in 1921, the Food and Drug Administration (FDA) has authorised around 100 …

[HTML][HTML] Peptides targeting HER2-positive breast cancer cells and applications in tumor imaging and delivery of chemotherapeutics

PA Cavallaro, M De Santo, EL Belsito, C Longobucco… - Nanomaterials, 2023 - mdpi.com
Breast cancer represents the most common cancer type and one of the major leading
causes of death in the female worldwide population. Overexpression of HER2, a …

Progress and perspectives on directing group-assisted palladium-catalysed C–H functionalisation of amino acids and peptides

S Shabani, Y Wu, HG Ryan, CA Hutton - Chemical Society Reviews, 2021 - pubs.rsc.org
Peptide modifications can unlock a variety of compounds with structural diversity and
abundant biological activity. In nature, peptide modifications, such as functionalisation at the …

In vitro genetic code reprogramming for the expansion of usable noncanonical amino acids

T Katoh, H Suga - Annual Review of Biochemistry, 2022 - annualreviews.org
Genetic code reprogramming has enabled us to ribosomally incorporate various
nonproteinogenic amino acids (npAAs) into peptides in vitro. The repertoire of usable npAAs …

Recent advances in sustainable organic transformations using methanol: expanding the scope of hydrogen-borrowing catalysis

LM Kabadwal, S Bera, D Banerjee - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The present review focuses on recent progress achieved from 2017 to March 2021 using
methanol as a C1-alkylating agent. A series of novel metal-catalyzed hydrogen-borrowing …

Asymmetric Synthesis of N‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination

P Yao, JR Marshall, Z Xu, J Lim… - Angewandte Chemie …, 2021 - Wiley Online Library
N‐Substituted α‐amino esters are widely used as chiral intermediates in a range of
pharmaceuticals. Here we report the enantioselective biocatalyic synthesis of N‐substituted …

Removal of unleaded gasoline from water by multi-walled carbon nanotubes

D Lico, D Vuono, C Siciliano, JB Nagy… - Journal of Environmental …, 2019 - Elsevier
This article displays an efficient and cost effective technique for the removal of unleaded
gasoline from water. Multi-walled carbon nanotubes (MWCNTs) were used as the sorbent …