Sweet new roles for protein glycosylation in prokaryotes

J Eichler, M Koomey - Trends in microbiology, 2017 - cell.com
Long-held to be a post-translational modification unique to Eukarya, it is now clear that both
Bacteria and Archaea also perform protein glycosylation, namely the covalent attachment of …

Transcriptional regulation in archaea: from individual genes to global regulatory networks

M Martinez-Pastor, PD Tonner… - Annual review of …, 2017 - annualreviews.org
Archaea are major contributors to biogeochemical cycles, possess unique metabolic
capabilities, and resist extreme stress. To regulate the expression of genes encoding these …

An archaeal histone-like protein regulates gene expression in response to salt stress

S Sakrikar, AK Schmid - Nucleic acids research, 2021 - academic.oup.com
Histones, ubiquitous in eukaryotes as DNA-packing proteins, find their evolutionary origins
in archaea. Unlike the characterized histone proteins of a number of methanogenic and …

Discovery of a novel transcriptional regulator of sugar catabolism in archaea

U Johnsen, M Ortjohann, A Reinhardt… - Molecular …, 2023 - Wiley Online Library
The haloarchaeon Haloferax volcanii degrades D‐glucose via the semiphosphorylative
Entner‐Doudoroff pathway and D‐fructose via a modified Embden‐Meyerhof pathway. Here …

A conserved transcription factor controls gluconeogenesis via distinct targets in hypersaline-adapted archaea with diverse metabolic capabilities

RK Hackley, A Vreugdenhil-Hayslette, CL Darnell… - Plos …, 2024 - journals.plos.org
Timely regulation of carbon metabolic pathways is essential for cellular processes and to
prevent futile cycling of intracellular metabolites. In Halobacterium salinarum, a hypersaline …

Detecting differential growth of microbial populations with Gaussian process regression

PD Tonner, CL Darnell, BE Engelhardt… - Genome …, 2017 - genome.cshlp.org
Microbial growth curves are used to study differential effects of media, genetics, and stress
on microbial population growth. Consequently, many modeling frameworks exist to capture …

The secondary metabolite hydrogen cyanide protects Pseudomonas aeruginosa against sodium hypochlorite-induced oxidative stress

WS da Cruz Nizer, ME Adams, V Inkovskiy… - Frontiers in …, 2023 - frontiersin.org
The high pathogenicity of Pseudomonas aeruginosa is attributed to the production of many
virulence factors and its resistance to several antimicrobials. Among them, sodium …

Phage-antibiotic synergy suppresses resistance emergence of Klebsiella pneumoniae by altering the evolutionary fitness

K Qin, X Shi, K Yang, Q Xu, F Wang, S Chen, T Xu… - Mbio, 2024 - journals.asm.org
Phage-antibiotic synergy (PAS) represents a superior treatment strategy for pathogen
infections with less probability of resistance development. Here, we aim to understand the …

Formulation of Chemically Defined Media and Growth Evaluation of Ligilactobacillus salivarius ZJ614 and Limosilactobacillus reuteri ZJ625

ID Kwoji, M Okpeku, MA Adeleke… - Frontiers in …, 2022 - frontiersin.org
Lactic acid bacteria are increasingly becoming important dietary supplements due to their
health benefits when consumed in adequate quantity. The increasing attention on these …

CdrS is a global transcriptional regulator influencing cell division in Haloferax volcanii

Y Liao, V Vogel, S Hauber, J Bartel, OS Alkhnbashi… - Mbio, 2021 - Am Soc Microbiol
Transcriptional regulators that integrate cellular and environmental signals to control cell
division are well known in bacteria and eukaryotes, but their existence is poorly understood …