Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

The immunology of host defence peptides: beyond antimicrobial activity

REW Hancock, EF Haney, EE Gill - Nature Reviews Immunology, 2016 - nature.com
Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

[HTML][HTML] Mechanisms and consequences of bacterial resistance to antimicrobial peptides

DI Andersson, D Hughes… - Drug Resistance Updates, 2016 - Elsevier
Cationic antimicrobial peptides (AMPs) are an intrinsic part of the human innate immune
system. Over 100 different human AMPs are known to exhibit broad-spectrum antibacterial …

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

JM Ageitos, A Sánchez-Pérez, P Calo-Mata… - Biochemical …, 2017 - Elsevier
Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

Defensins: The natural peptide antibiotic

X Gao, J Ding, C Liao, J Xu, X Liu, W Lu - Advanced drug delivery reviews, 2021 - Elsevier
Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

Defensins: antimicrobial peptides of innate immunity

T Ganz - Nature reviews immunology, 2003 - nature.com
The production of natural antibiotic peptides has emerged as an important mechanism of
innate immunity in plants and animals. Defensins are diverse members of a large family of …

[HTML][HTML] Antimicrobial peptides–unleashing their therapeutic potential using nanotechnology

S Gera, E Kankuri, K Kogermann - Pharmacology & Therapeutics, 2022 - Elsevier
Antimicrobial peptides (AMPs) are potent, mostly cationic, and amphiphilic broad-spectrum
host defense antimicrobials that are produced by all organisms ranging from prokaryotes to …

[HTML][HTML] Antimicrobial peptides and the gut microbiome in inflammatory bowel disease

J Gubatan, DR Holman, CJ Puntasecca… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Antimicrobial peptides (AMP) are highly diverse and dynamic molecules that are expressed
by specific intestinal epithelial cells, Paneth cells, as well as immune cells in the …

Mammalian defensins in the antimicrobial immune response

ME Selsted, AJ Ouellette - Nature immunology, 2005 - nature.com
Defensins are peptidic components of the innate immune system of plants and animals. In
mammals, defensins have evolved to have a central function in the host defense properties …

Antimicrobial peptides: general overview and clinical implications in human health and disease

E Guaní-Guerra, T Santos-Mendoza, SO Lugo-Reyes… - Clinical …, 2010 - Elsevier
Antimicrobial peptides (AMPs) are evolutionarily conserved molecules involved in the
defense mechanisms of a wide range of organisms. Produced in bacteria, insects, plants …