The nucleolus as a multiphase liquid condensate
The nucleolus is the most prominent nuclear body and serves a fundamentally important
biological role as a site of ribonucleoprotein particle assembly, primarily dedicated to …
biological role as a site of ribonucleoprotein particle assembly, primarily dedicated to …
Methods for map** 3D chromosome architecture
R Kempfer, A Pombo - Nature Reviews Genetics, 2020 - nature.com
Determining how chromosomes are positioned and folded within the nucleus is critical to
understanding the role of chromatin topology in gene regulation. Several methods are …
understanding the role of chromatin topology in gene regulation. Several methods are …
Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers
The relationships between chromosomal compartmentalization, chromatin state and function
are poorly understood. Here by profiling long-range contact frequencies in HCT116 colon …
are poorly understood. Here by profiling long-range contact frequencies in HCT116 colon …
The role of 3D genome organization in development and cell differentiation
H Zheng, W ** the spatial organization of the genome
The spatial organization of the genome into compartments and topologically associated
domains can have an important role in the regulation of gene expression. But could gene …
domains can have an important role in the regulation of gene expression. But could gene …