The cytoskeleton is a network of interconnected protein filaments, which provide a three‐
dimensional scaffold for cells. Remodeling of the cytoskeleton is important for key cellular …

The essential functions required for mitotic spindle assembly and chromosome biorientation
and segregation are not fully understood, despite extensive study. To illuminate the …

Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary
Gergely, Eileen O'Toole, Ammon Crapo, Loren Hough, Richard McIntosh, Matthew Glaser …

Microtubule-crosslinking motor proteins, which slide antiparallel microtubules, are required
for the remodeling of microtubule networks. Hitherto, all microtubule-crosslinking motors …

Current understanding of how contractility emerges in disordered actomyosin networks of
nonmuscle cells is still largely based on the intuition derived from earlier works on muscle …

Background At the beginning of mitosis, the cell forms a spindle made of microtubules and
associated proteins to segregate chromosomes. An important part of spindle architecture is …

Antiparallel microtubule bundles are essential structural elements of many cytoskeletal
structures, for instance, the mitotic spindle. Sliding of microtubules relative to each other can …

The mitotic spindle, a micromachine composed of microtubules and associated proteins,
plays a pivotal role in ensuring the accurate segregation of chromosomes. During spindle …

During mitosis, microtubules form a spindle, which is responsible for proper segregation of
the genetic material. A common structural element in a mitotic spindle is a parallel bundle …

Protein motors, such as kinesins and dyneins, bind to a microtubule and travel along it in a
specific direction. Previously, it was thought that the directionality for a given motor was …