Glioblastoma and other primary brain malignancies in adults: a review

LR Schaff, IK Mellinghoff - Jama, 2023 - jamanetwork.com
Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …

Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours

C Horbinski, T Berger, RJ Packer, PY Wen - Nature Reviews Neurology, 2022 - nature.com
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …

CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2015–2019

QT Ostrom, M Price, C Neff, G Cioffi, KA Waite… - Neuro …, 2022 - academic.oup.com
Abstract The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration
with the Centers for Disease Control and Prevention and the National Cancer Institute, is the …

[HTML][HTML] EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

M Weller, M van den Bent, M Preusser… - Nature reviews Clinical …, 2021 - nature.com
In response to major changes in diagnostic algorithms and the publication of mature results
from various large clinical trials, the European Association of Neuro-Oncology (EANO) …

CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013–2017

QT Ostrom, N Patil, G Cioffi, K Waite, C Kruchko… - Neuro …, 2020 - academic.oup.com
Abstract The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration
with the Centers for Disease Control (CDC) and National Cancer Institute (NCI), is the …

CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2014–2018

QT Ostrom, G Cioffi, K Waite, C Kruchko… - Neuro …, 2021 - academic.oup.com
Abstract The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration
with the Centers for Disease Control and Prevention (CDC) and National Cancer Institute …

Mechanisms and therapeutic implications of hypermutation in gliomas

M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu… - Nature, 2020 - nature.com
A high tumour mutational burden (hypermutation) is observed in some gliomas,,,–; however,
the mechanisms by which hypermutation develops and whether it predicts the response to …

World Health Organization 2021 classification of central nervous system tumors and implications for therapy for adult-type gliomas: a review

TR Berger, PY Wen, M Lang-Orsini… - JAMA …, 2022 - jamanetwork.com
Importance Previous histologic classifications of brain tumors have been limited by
discrepancies in diagnoses reported by neuropathologists and variability in outcomes and …

Context is everything: aneuploidy in cancer

U Ben-David, A Amon - Nature Reviews Genetics, 2020 - nature.com
Cancer is driven by multiple types of genetic alterations, which range in size from point
mutations to whole-chromosome gains and losses, known as aneuploidy. Chromosome …

Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised …

MJ van den Bent, CMS Tesileanu, W Wick… - The Lancet …, 2021 - thelancet.com
Background The CATNON trial investigated the addition of concurrent, adjuvant, and both
current and adjuvant temozolomide to radiotherapy in adults with newly diagnosed 1p/19q …