Extracellular vesicles (EVs), including exosomes (30–150 nm) and microvesicles (100–1500
nm), play important roles in mediating cell-cell communication. Such particles package …

The prevalence of pathogenic viruses is a serious issue as they pose a constant threat to
both the poultry industry and to human health. To prevent these viral infections an …

Human MxA protein belongs to the superfamily of dynamin-like large GTPases that are
involved in intracellular membrane trafficking. MxA is induced by interferons-α/β (IFN-α/β) …

To identify pathways controlling prostate cancer metastasis we performed differential display
analysis of the human prostate carcinoma cell line PC-3 and its highly metastatic derivative …

Problem Dairy cattle suffer from high percentages of early embryonic loss, and therefore, it is
critical to study the function of the uterus at this time. We hypothesize that the antiviral …

The interferon-induced Mx proteins of vertebrates are dynamin-like GTPases, some isoforms
of which can additionally inhibit the life cycle of certain RNA viruses. Here we show that the …

Background Chicken Mx belongs to the Mx family of interferon-induced dynamin-like
GTPases, which in some species possess potent antiviral properties. Conflicting data exist …

There is confusion about the role that IFN-α plays in the pathogenesis of pulmonary arterial
hypertension (PAH) with different investigators reporting a causative or a protective role …

Mx proteins are a group of interferon-induced GTPases whose expression has been
demonstrated in a number of human viral infections and in some idiopathic inflammatory …

Problem Embryonic loss is a major contributor to infertility. Understanding factors affecting
embryonic loss will help increase fertility. Method of study We investigated if ovine Mx1 …