Non-transdermal microneedles for advanced drug delivery

KJ Lee, MJ Goudie, P Tebon, W Sun, Z Luo… - Advanced drug delivery …, 2020 - Elsevier
Microneedles (MNs) have been used to deliver drugs for over two decades. These platforms
have been proven to increase transdermal drug delivery efficiency dramatically by …

Nanomedicine for Diagnosis and Treatment of Atherosclerosis

J Cheng, H Huang, Y Chen, R Wu - Advanced Science, 2023 - Wiley Online Library
With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …

Lipophilic NO‐driven nanomotors as drug balloon coating for the treatment of atherosclerosis

X Tang, L Chen, Z Wu, Y Li, J Zeng, W Jiang, W Lv… - Small, 2023 - Wiley Online Library
Drug‐coated balloons (DCB) intervention is an important approach for the treatment of
atherosclerosis (AS). However, this therapeutic approach has the drawbacks of poor drug …

[HTML][HTML] Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment

L Huang, H Fang, T Zhang, B Hu, S Liu, F Lv, Z Zeng… - Bioactive Materials, 2023 - Elsevier
Drug-eluting balloon (DEB) angioplasty has emerged as an effective treatment for
cardiovascular and cerebrovascular diseases. However, distal embolism and late lumen …

Recent advances in microneedle designs and their applications in drug and cosmeceutical delivery

R Parhi - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Transdermal drug delivery (TDD) was initially limited to fewer therapeutic agents due to the
requirements of suitable physicochemical and biological properties for passage across the …

Polymer-based microneedle composites for enhanced non-transdermal drug delivery

B Mbituyimana, G Ma, Z Shi, G Yang - Applied Materials Today, 2022 - Elsevier
The applications of microneedles (MNs) are becoming popular with the promise of efficient
and advanced drug delivery. MNs were developed to overcome the limitations of …

Microneedle drug eluting balloon for enhanced drug delivery to vascular tissue

KJ Lee, JY Lee, SG Lee, SH Park, JJ Lee… - Journal of Controlled …, 2020 - Elsevier
High rates of restenosis and neointimal formation have driven increasing interest in the
application of drug eluting balloons (DEB) as counteractive measures for intraluminal drug …

Investigating balloon-vessel contact pressure patterns in angioplasty: In silico insights for drug-coated balloons

E Stratakos, L Antonini, G Poletti, F Berti… - Annals of Biomedical …, 2023 - Springer
Abstract Drug-Coated Balloons have shown promising results as a minimally invasive
approach to treat stenotic arteries, but recent animal studies have revealed limited, non …

Understudied factors in drug‐coated balloon design and evaluation: A biophysical perspective

T Shazly, WM Torres, EA Secemsky… - Bioengineering & …, 2023 - Wiley Online Library
Drug‐coated balloon (DCB) percutaneous interventional therapy allows for durable
reopening of the narrowed lumen via physical tissue expansion and local anti‐restenosis …

Research progress on detachable microneedles for advanced applications

SH Park, KJ Lee, WH Ryu - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
ABSTRACT Introduction Microneedles (MNs) have undergone great advances in
transdermal drug delivery, and commercialized MN applications are currently available in …