Host-directed therapies: modulating inflammation to treat tuberculosis
Following infection with Mycobacterium tuberculosis, the causative agent of tuberculosis
(TB), most human hosts are able to contain the infection and avoid progression to active TB …
(TB), most human hosts are able to contain the infection and avoid progression to active TB …
Nanocarriers: A successful tool to increase solubility, stability and optimise bioefficacy of natural constituents
Natural products are fascinating molecules in drug discovery for their exciting structure
variability and also for their interaction with various targets. Drugs multi-targeting effect …
variability and also for their interaction with various targets. Drugs multi-targeting effect …
[6]-Gingerol exhibits potent anti-mycobacterial and immunomodulatory activity against tuberculosis
The currently available anti-tuberculosis treatment (ATT) comprises exclusively of anti-
bacterial drugs, is very lengthy, has adverse side effects on the host and leads to the …
bacterial drugs, is very lengthy, has adverse side effects on the host and leads to the …
The advances in adjuvant therapy for tuberculosis with immunoregulatory compounds
J Mi, X Wu, J Liang - Frontiers in Microbiology, 2024 - frontiersin.org
Tuberculosis (TB) is a chronic bacterial disease, as well as a complex immune disease. The
occurrence, development, and prognosis of TB are not only related to the pathogenicity of …
occurrence, development, and prognosis of TB are not only related to the pathogenicity of …
The war against tuberculosis: A review of natural compounds and their derivatives
M Maiolini, S Gause, J Taylor, T Steakin, G Shipp… - Molecules, 2020 - mdpi.com
Tuberculosis (TB), caused by the bacterial organism Mycobacterium tuberculosis, pose a
major threat to public health, especially in middle and low-income countries. Worldwide in …
major threat to public health, especially in middle and low-income countries. Worldwide in …
Tuberculosis: The success tale of less explored dormant Mycobacterium tuberculosis
A Verma, A Ghoshal, VP Dwivedi… - Frontiers in Cellular and …, 2022 - frontiersin.org
Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that predominantly affects
the alveolar macrophages in the respiratory tract. Upon infection, the activation of TLR2 and …
the alveolar macrophages in the respiratory tract. Upon infection, the activation of TLR2 and …
Therapeutic potential of curcumin as an antimycobacterial agent
N Barua, AK Buragohain - Biomolecules, 2021 - mdpi.com
Curcumin is the principal curcuminoid obtained from the plant Curcuma longa and has been
extensively studied for its biological and chemical properties. Curcumin displays a vast …
extensively studied for its biological and chemical properties. Curcumin displays a vast …
Macrophage targeted polymeric curcumin nanoparticles limit intracellular survival of Mycobacterium tuberculosis through induction of autophagy and augment anti …
PK Gupta, P Jahagirdar, D Tripathi… - Frontiers in …, 2023 - frontiersin.org
Rapid emergence of antibiotic resistance in tuberculosis has left us with limited resources to
treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the …
treat and manage multi drug resistant (MDR) cases of tuberculosis, prompting the …
Nanosized Drug Delivery Systems to Fight Tuberculosis
T Bourguignon, JA Godinez-Leon, R Gref - Pharmaceutics, 2023 - mdpi.com
Tuberculosis (TB) is currently the second deadliest infectious disease. Existing
antitubercular therapies are long, complex, and have severe side effects that result in low …
antitubercular therapies are long, complex, and have severe side effects that result in low …
Potential application of nanotechnology in the treatment, diagnosis, and prevention of schistosomiasis
Schistosomiasis is one of the neglected tropical diseases that affect millions of people
worldwide. Globally, it affects economically poor countries, typically due to a lack of proper …
worldwide. Globally, it affects economically poor countries, typically due to a lack of proper …