Nonreplicative functions of the origin recognition complex
Origin recognition complex (ORC), a heteromeric six-subunit complex, is the central
component of the eukaryotic pre-replication complex. Recent data from yeast, frogs, flies and …
component of the eukaryotic pre-replication complex. Recent data from yeast, frogs, flies and …
Destabilization of the replication fork protection complex disrupts meiotic chromosome segregation
The replication fork protection complex (FPC) coordinates multiple processes that are crucial
for unimpeded passage of the replisome through various barriers and difficult to replicate …
for unimpeded passage of the replisome through various barriers and difficult to replicate …
Deletion of Orc4 during oogenesis severely reduces polar body extrusion and blocks zygotic DNA replication
H Nguyen, H Wu, A Ung, Y Yamazaki… - Biology of …, 2022 - academic.oup.com
Origin recognition complex subunit 4 (ORC4) is a DNA-binding protein required for DNA
replication. During oocyte maturation, after the last oocyte DNA replication step and before …
replication. During oocyte maturation, after the last oocyte DNA replication step and before …
The role of ORC4 in enucleation of murine erythroleukemia (MEL) cells is similar to that in oocyte polar body extrusion
H Nguyen, A Ung, WS Ward - Systems biology in reproductive …, 2020 - Taylor & Francis
ABSTRACT The Origin Replication Complex subunit 4 (ORC4) is one in six subunits of the
Origin Replication Complexes (ORCs) which is essential for initiating licensing at DNA …
Origin Replication Complexes (ORCs) which is essential for initiating licensing at DNA …
Spatial and temporal resolution of mORC4 fluorescent variants reveals structural requirements for achieving higher order self-association and pronuclei entry
H Nguyen, WS Ward, NG James - Methods and applications in …, 2019 - iopscience.iop.org
Abstract The Origin Replication Complex (ORC), which is a multi-subunit protein complex
composed of six proteins ORC1–6, is essential for initiating licensing at DNA replication …
composed of six proteins ORC1–6, is essential for initiating licensing at DNA replication …
The Role of N-WASP in ORC4 Mediated Polar Body Extrusion
DCO Elento - 2020 - search.proquest.com
Oocyte meiosis is completed though two asymmetric cellular divisions, where the oocyte
extrudes half of its DNA two times, into two smaller daughter cells called polar bodies. N …
extrudes half of its DNA two times, into two smaller daughter cells called polar bodies. N …
The Licensing Protein ORC4 is Required for Polar Body Extrusion During Murine Meiosis.
HT Nguyen - 2017 - scholarspace.manoa.hawaii.edu
Abstract Six proteins, ORC1-6, make up the origin recognition complex (ORC) that initiates
licensing of the DNA replication origin. We have previously shown that subunit ORC1 …
licensing of the DNA replication origin. We have previously shown that subunit ORC1 …