Neuronal cells rearrangement during aging and neurodegenerative disease: metabolism, oxidative stress and organelles dynamic

V Castelli, E Benedetti, A Antonosante… - Frontiers in molecular …, 2019 - frontiersin.org
Brain cells normally respond adaptively to oxidative stress or bioenergetic challenges,
resulting from ongoing activity in neuronal circuits. During aging and in neurodegenerative …

Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies

S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds

M Nassiri‐Asl, H Hosseinzadeh - Phytotherapy Research: An …, 2009 - Wiley Online Library
Vitis vinifera, known as the grapevine, is native to southern Europe and Western Asia. Grape
seed and skin contain several active components including flavonoids, polyphenols …

Oxidative stress and aberrant signaling in aging and cognitive decline

W Dröge, HM Schipper - Aging cell, 2007 - Wiley Online Library
Brain aging is associated with a progressive imbalance between antioxidant defenses and
intracellular concentrations of reactive oxygen species (ROS) as exemplified by increases in …

Examining the impact of grape consumption on brain metabolism and cognitive function in patients with mild decline in cognition: A double-blinded placebo controlled …

J Lee, N Torosyan, DH Silverman - Experimental gerontology, 2017 - Elsevier
Background Natural compounds in grapes such as resveratrol are known for their
antioxidant and anti-inflammatory properties. Some studies have shown a potential role for …

The protective role of plant biophenols in mechanisms of Alzheimer's disease

SH Omar, CJ Scott, AS Hamlin, HK Obied - The Journal of nutritional …, 2017 - Elsevier
Self-assembly of amyloid beta peptide (Aβ) into the neurotoxic oligomers followed by fibrillar
aggregates is a defining characteristic of Alzheimer's disease (AD). Several lines of …

Gastrointestinal stability and bioavailability of (poly) phenolic compounds following ingestion of Concord grape juice by humans

A Stalmach, CA Edwards… - Molecular nutrition & …, 2012 - Wiley Online Library
The in vitro gastrointestinal stability of (poly) phenolic compounds in Concord grape juice
was compared with recoveries in ileal fluid after the ingestion of the juice by ileostomists …

Grape (Vitis vinifera L.) phytochemicals and their biochemical protective mechanisms against leading pathologies

U Majeed, A Shafi, H Majeed, K Akram, X Liu, J Ye… - Food Chemistry, 2023 - Elsevier
The intake of herbal dietary constituents, mostly fruits and vegetables, have been
considered well-known to prevent pathologies (degenerative diseases). Consumer …

[HTML][HTML] A review study on medicinal plants used in the treatment of learning and memory impairments

N Jivad, Z Rabiei - Asian Pacific Journal of Tropical Biomedicine, 2014 - Elsevier
Alzheimer's disease (AD) is a progressive brain disorder that gradually impairs the person's
memory and ability to learn, reasoning, judgment, communication and daily activities. AD is …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …