Formation of γ-H2AX in response to DNA double stranded breaks (DSBs) provides the basis
for a sensitive assay of DNA damage in human biopsies. The review focuses on the …

Ionizing radiation is often regarded as an element of danger. But, danger responses on the
cellular and molecular level are often beneficial with regard to the induction of anti‐tumor …

One of the earliest cellular responses to DNA double strand breaks (DSBs) is the
phosphorylation of the core histone protein H2AX (termed γH2AX). Persistent γH2AX is the …

Ionizing radiation is a known human carcinogen that can induce a variety of biological
effects depending on the physical nature, duration, doses and dose-rates of exposure …

Following a mass-casualty nuclear disaster, effective medical triage has the potential to save
tens of thousands of lives. In order to best use the available scarce resources, there is an …

Effective planning for the medical response to a radiological or nuclear accident is complex.
Because of limited resources for medical countermeasures, the key would be to accurately …

There is increasing evidence showing a close relationship between human radiation
sensitivity and age-related health effects including cancer. Individuals exposed to ionizing …

Accidental radiation exposure is a threat to human health that necessitates effective clinical
planning and diagnosis. Minimally invasive biomarkers that can predict long-term radiation …

DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We
hypothesized that monitoring the expression of DNA repair-associated genes would …

A large-scale malicious or accidental radiological event can expose vast numbers of people
to ionizing radiation. The dicentric chromosome (DCA) and cytokinesis-block micronucleus …