Platelets are among the most abundant cells within the circulation. Given that the platelet
lifespan is 7 to 10 days in humans, a constant production of around 100 billion platelets per …

Immunoactinopathies caused by mutations in actin‐related proteins are a growing group of
inborn errors of immunity (IEI). Immunoactinopathies are caused by a dysregulated actin …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. The inflammatory cytokine storm causes systemic organ damage, especially acute …

Platelets prevent blood loss during vascular injury and contribute to thrombus formation in
cardiovascular disease. Beyond these classical roles, platelets are critical for the host …

Vascular sequelae following (SARS-CoV-2 coronavirus disease)(COVID)-19 infection are
considered as “Long Covid (LC)” disease, when occurring 12 weeks after the original …

Objective Our aim was to assess systemic immune-inflammation index (SII) and NT-proBNP
value either in singly or in combination to predict acute ST-elevation myocardial infarction …

Platelets, anucleate blood components, represent the major cell type involved in the
regulation of hemostasis and thrombosis. In addition to performing haemostatic roles …

Myocardial ischemia–reperfusion injury (MIRI) is a major hindrance to the success of cardiac
reperfusion therapy. Although increased neutrophil infiltration is a hallmark of MIRI, the …

Background Chronic low-grade inflammation is the common mechanism of both
atherosclerosis and type 2 diabetes mellitus (T2DM), and systemic immune-inflammation …

Context Preoperative inflammatory markers, such as the neutrophil-lymphocyte ratio (NLR),
platelet-lymphocyte ratio (PLR), and lymphocyte-monocyte ratio (LMR), have recently been …