Prevalence, severity and mortality associated with COPD and smoking in patients with COVID-19: a rapid systematic review and meta-analysis

JS Alqahtani, T Oyelade, AM Aldhahir, SM Alghamdi… - PloS one, 2020 - journals.plos.org
Background Coronavirus disease 2019 (COVID-19) is an evolving infectious disease that
dramatically spread all over the world in the early part of 2020. No studies have yet …

Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

An updated definition and severity classification of chronic obstructive pulmonary disease exacerbations: the Rome proposal

BR Celli, LM Fabbri, SD Aaron, A Agusti… - American journal of …, 2021 - atsjournals.org
Over 200 years ago, René Laennec published the first description of emphysema, an
important pathobiological element of what is today known as chronic obstructive pulmonary …

Factors determining the diffusion of COVID-19 and suggested strategy to prevent future accelerated viral infectivity similar to COVID

M Coccia - Science of the Total Environment, 2020 - Elsevier
This study has two goals. The first is to explain the geo-environmental determinants of the
accelerated diffusion of COVID-19 that is generating a high level of deaths. The second is to …

Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations

AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - pmc.ncbi.nlm.nih.gov
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are episodes of
symptom worsening which have significant adverse consequences for patients …

Update on clinical aspects of chronic obstructive pulmonary disease

BR Celli, JA Wedzicha - New England Journal of Medicine, 2019 - Mass Medical Soc
Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary

CF Vogelmeier, GJ Criner, FJ Martinez… - American journal of …, 2017 - atsjournals.org
This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

The lung microbiome: progress and promise

SA Whiteside, JE McGinniss, RG Collman - The Journal of Clinical …, 2021 - jci.org
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro

KH Benam, R Villenave, C Lucchesi, A Varone… - Nature …, 2016 - nature.com
Here we describe the development of a human lung'small airway-on-a-chip'containing a
differentiated, mucociliary bronchiolar epithelium and an underlying microvascular …

Inflammatory endotypes in COPD

PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …