[HTML][HTML] Therapeutic versatility of resveratrol derivatives

W Nawaz, Z Zhou, S Deng, X Ma, X Ma, C Li, X Shu - Nutrients, 2017 - mdpi.com
Resveratrol, a natural phytoalexin, exhibits a remarkable range of biological activities, such
as anticancer, cardioprotective, neuroprotective and antioxidant properties. However, the …

Resveratrol and related stilbenes: their anti-aging and anti-angiogenic properties

KM Kasiotis, H Pratsinis, D Kletsas… - Food and Chemical …, 2013 - Elsevier
Dietary stilbenes comprise a class of natural compounds that display significant biological
activities of medicinal interest. Among them, their antioxidant, anti-aging and anti …

Resveratrol and derivatives for the prevention and treatment of cancer

S Fulda - Drug discovery today, 2010 - Elsevier
Resveratrol, a naturally derived stilbene that exists in various foods and beverages, has
attracted increasing attention over the past decade because of its multiple beneficial …

[HTML][HTML] Resveratrol derivatives: Synthesis and their biological activities

L Grau, R Soucek, MD Pujol - European Journal of Medicinal Chemistry, 2023 - Elsevier
Resveratrol, a natural compound known especially for its antioxidant properties and
protective action, opens the door for both it and its structural derivatives to be considered not …

Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: A mechanistic review

AA Arabzadeh, T Mortezazadeh, T Aryafar… - Cancer cell …, 2021 - Springer
Glioblastoma, WHO grade IV astrocytoma, is the most aggressive type of brain tumors.
These cancerous cells have a rapid growth rate, tendency to penetrate vital brain structures …

A systematic review of the potential chemoprotective effects of resveratrol on doxorubicin‐induced cardiotoxicity: Focus on the antioxidant, antiapoptotic, and anti …

LF Hu, HR Lan, XM Li, KT ** - Oxidative medicine and cellular …, 2021 - Wiley Online Library
Purpose. Although doxorubicin chemotherapeutic drug is commonly used to treat various
solid and hematological tumors, its clinical use is restricted because of its adverse effects on …

[HTML][HTML] Insights on the effects of resveratrol and some of its derivatives in cancer and autoimmunity: a molecule with a dual activity

E Gianchecchi, A Fierabracci - Antioxidants, 2020 - mdpi.com
In recent years, the interest in natural compounds exerting immunoregulatory effects has
enormously increased. Among these, the polyphenol resveratrol, found in a variety of foods …

Resveratrol attenuates diabetic nephropathy via modulating angiogenesis

D Wen, X Huang, M Zhang, L Zhang, J Chen, Y Gu… - PloS one, 2013 - journals.plos.org
Angiogenesis plays an important role in the pathogenesis of diabetic nephropathy (DN). In
the present study, we investigated the therapeutic potential of resveratrol, a polyphenol with …

Resveratrol blocks diabetes‐induced early vascular lesions and vascular endothelial growth factor induction in mouse retinas

YH Kim, YS Kim, GS Roh, WS Choi… - Acta …, 2012 - Wiley Online Library
Purpose: Vessel leakage and loss of pericytes are early signs of diabetic retinopathy (DR),
which leads to vision loss. Upregulation of the vascular endothelial growth factor (VEGF) …

Resveratrol enhances antitumor activity of TRAIL in prostate cancer xenografts through activation of FOXO transcription factor

S Ganapathy, Q Chen, KP Singh, S Shankar… - PloS one, 2010 - journals.plos.org
Background Resveratrol (3, 4′, 5 tri-hydroxystilbene), a naturally occurring polyphenol,
exhibits anti-inflammatory, antioxidant, cardioprotective and antitumor activities. We have …