EPR in-cell spin-labeling was applied to CueR in E. coli. The methodology employed a Cu
(II)-NTA complexed with dHis. High resolved in-cell distance distributions were obtained …

Proliferating cell nuclear antigen (PCNA) is the key regulator of human DNA metabolism.
One important interaction partner is p15, involved in DNA replication and repair. Targeting …

Reactive chlorine species (RCS), particularly hypochlorous acid (HOCl), are powerful
antimicrobial oxidants generated by biological pathways and chemical syntheses …

The L84S mutation has been observed frequently in the ORF8 protein of SARS-CoV-2,
which is an accessory protein involved in various important functions such as virus …

β-carbonic anhydrases (βCA) accelerate the equilibrium formation between CO2 and
carbonate. Two plant βCA isoforms are targeted to the chloroplast and represent abundant …

Copper, an essential metal for various cellular processes, requires tight regulation to prevent
cytotoxicity. Intracellular pathways crucial for maintaining optimal copper levels involve …

Copper's essentiality and toxicity mean it requires a sophisticated regulation system for its
acquisition, cellular distribution and excretion, which until now has remained elusive …

Abstract PESs of H 2 OH 2 S mixed clusters up to tetramer have been investigated to study
how replacement of conventional H-bonds by sulfur-centered H-bonds systematically …

Atox1 is a human copper metallochaperone that is responsible for transferring copper ions
from the main human copper transporter, hCtr1, to ATP7A/B in the Golgi apparatus. Atox1 …

The copper chaperone Atox1, which is featured by a peculiar CxxC metal-binding motif, is a
protein involved in copper trafficking to the Golgi organelle, allowing the delivery of copper …