[HTML][HTML] In-vivo 31P-MRS of skeletal muscle and liver: a way for non-invasive assessment of their metabolism
In addition to direct assessment of high energy phosphorus containing metabolite content
within tissues, phosphorus magnetic resonance spectroscopy (31 P-MRS) provides options …
within tissues, phosphorus magnetic resonance spectroscopy (31 P-MRS) provides options …
Exercise: a molecular tool to boost muscle growth and mitochondrial performance in heart failure?
KT Nijholt, PI Sánchez‐Aguilera… - European journal of …, 2022 - Wiley Online Library
Impaired exercise capacity is the key symptom of heart failure (HF) and is associated with
reduced quality of life and higher mortality rates. Unfortunately, current therapies, although …
reduced quality of life and higher mortality rates. Unfortunately, current therapies, although …
31P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations
Skeletal muscle phosphorus‐31 31P MRS is the oldest MRS methodology to be applied to
in vivo metabolic research. The technical requirements of 31P MRS in skeletal muscle …
in vivo metabolic research. The technical requirements of 31P MRS in skeletal muscle …
Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled …
Background 'Long COVID'describes persistent symptoms, commonly fatigue, lasting beyond
12 weeks following SARS-CoV-2 infection. Potential causes include reduced mitochondrial …
12 weeks following SARS-CoV-2 infection. Potential causes include reduced mitochondrial …
Skeletal Muscle Abnormalities and Iron Deficiency in Chronic Heart Failure: An Exercise 31P Magnetic Resonance Spectroscopy Study of Calf Muscle
V Melenovsky, K Hlavata, P Sedivy… - Circulation: Heart …, 2018 - Am Heart Assoc
Background: Heart failure (HF) is often associated with iron deficiency (ID). Skeletal muscle
abnormalities are common in HF, but the potential role of ID in this phenomenon is unclear …
abnormalities are common in HF, but the potential role of ID in this phenomenon is unclear …
1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID
LEM Finnigan, MP Cassar, M Jafarpour, A Sultana… - Radiology, 2024 - pubs.rsna.org
Background Emerging evidence suggests mitochondrial dysfunction may play a role in the
fatigue experienced by individuals with post–COVID-19 condition (PCC), commonly called …
fatigue experienced by individuals with post–COVID-19 condition (PCC), commonly called …
Dynamic 31P–MRSI using spiral spectroscopic imaging can map mitochondrial capacity in muscles of the human calf during plantar flexion exercise at 7 T
Abstract Phosphorus MRSI (31P–MRSI) using a spiral‐trajectory readout at 7 T was
developed for high temporal resolution map** of the mitochondrial capacity of exercising …
developed for high temporal resolution map** of the mitochondrial capacity of exercising …
Phosphorus magnetic resonance spectroscopy and imaging (31P-MRS/MRSI) as a window to brain and muscle metabolism: A review of the methods
Phosphorus magnetic resonance spectroscopy and spectroscopic imaging (31 P-
MRS/MRSI) non-invasively provide very important information regarding energy metabolism …
MRS/MRSI) non-invasively provide very important information regarding energy metabolism …
Skeletal muscle ATP synthesis and cellular H+ handling measured by localized 31P-MRS during exercise and recovery
GB Fiedler, AI Schmid, S Goluch, K Schewzow… - Scientific reports, 2016 - nature.com
Abstract 31P magnetic resonance spectroscopy (MRS) is widely used for non-invasive
investigation of muscle metabolism dynamics. This study aims to extend knowledge on …
investigation of muscle metabolism dynamics. This study aims to extend knowledge on …
Modifier genes in SCN1A‐related epilepsy syndromes
IM de Lange, F Mulder, R van't Slot… - Molecular genetics & …, 2020 - Wiley Online Library
Background SCN1A is one of the most important epilepsy‐related genes, with pathogenic
variants leading to a range of phenotypes with varying disease severity. Different modifying …
variants leading to a range of phenotypes with varying disease severity. Different modifying …