The multifarious roles of Tol-Pal in Gram-negative bacteria

J Szczepaniak, C Press… - FEMS Microbiology …, 2020 - academic.oup.com
In the 1960s several groups reported the isolation and preliminary genetic map** of
Escherichia coli strains tol erant towards the action of colicins. These pioneering studies kick …

Bacterial outer membrane constriction

AJF Egan - Molecular microbiology, 2018 - Wiley Online Library
The outer membrane of Gram‐negative bacteria is a crucial permeability barrier allowing the
cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of …

Development of a vitamin B5 hyperproducer in Escherichia coli by multiple metabolic engineering

F Song, Z Qin, K Qiu, Z Huang, L Wang, H Zhang… - Metabolic …, 2024 - Elsevier
Vitamin B 5 [D-pantothenic acid (D-PA)] is an essential water-soluble vitamin that is widely
used in the food and feed industries. Currently, the relatively low fermentation efficiency …

The mechanism of force transmission at bacterial focal adhesion complexes

LM Faure, JB Fiche, L Espinosa, A Ducret… - Nature, 2016 - nature.com
Various rod-shaped bacteria mysteriously glide on surfaces in the absence of appendages
such as flagella or pili. In the deltaproteobacterium Myxococcus xanthus, a putative gliding …

Tunable force transduction through the Escherichia coli cell envelope

DP Williams-Jones, MN Webby… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane (OM) of Gram-negative bacteria is not energised and so processes
requiring a driving force must connect to energy-transduction systems in the inner …

Ton motor conformational switch and peptidoglycan role in bacterial nutrient uptake

M Zinke, M Lejeune, A Mechaly, B Bardiaux… - Nature …, 2024 - nature.com
Active nutrient uptake is fundamental for survival and pathogenicity of Gram-negative
bacteria, which operate a multi-protein Ton system to transport essential nutrients like metals …

Identification of Genes Involved in Biogenesis of Outer Membrane Vesicles (OMVs) in Salmonella enterica Serovar Typhi

J Nevermann, A Silva, C Otero, DP Oyarzún… - Frontiers in …, 2019 - frontiersin.org
Outer membrane vesicles (OMVs) are nano-sized proteoliposomes discharged from the cell
envelope of Gram-negative bacteria. OMVs normally contain toxins, enzymes and other …

A new class of biological ion-driven rotary molecular motors with 5: 2 symmetry

M Rieu, R Krutyholowa, NMI Taylor… - Frontiers in …, 2022 - frontiersin.org
Several new structures of three types of protein complexes, obtained by cryo-electron
microscopy (cryo-EM) and published between 2019 and 2021, identify a new family of …

Binding from both sides: TolR and full-length OmpA bind and maintain the local structure of the E. coli cell wall

AT Boags, F Samsudin, S Khalid - Structure, 2019 - cell.com
We present a molecular modeling and simulation study of the E. coli cell envelope, with a
particular focus on the role of TolR, a native protein of the E. coli inner membrane, in …

[HTML][HTML] Computational microbiology of bacteria: Advancements in molecular dynamics simulations

S Khalid, AF Brandner, N Juraschko, KE Newman… - Structure, 2023 - cell.com
Microbiology is traditionally considered within the context of wet laboratory methodologies.
Computational techniques have a great potential to contribute to microbiology. Here, we …