Current issues and perspectives in small rodent magnetic resonance imaging using clinical MRI scanners

MA Brockmann, A Kemmling, C Groden - Methods, 2007 - Elsevier
Small rodents such as mice and rats are frequently used in animal experiments for several
reasons. In the past, animal experiments were frequently associated with invasive methods …

Preclinical molecular imaging using PET and MRI

G Wolf, N Abolmaali - Molecular Imaging in Oncology, 2012 - Springer
Molecular imaging fundamentally changes the way we look at cancer. Imaging paradigms
are now shifting away from classical morphological measures towards the assessment of …

Diffusion‐weighted MRI of hepatic tumor in rats: Comparison between in vivo and postmortem imaging acquisitions

X Sun, H Wang, F Chen, F De Keyzer… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To determine the feasibility of in vivo diffusion‐weighted imaging (DWI) to
distinguish between normal liver, viable tumor and necrosis compared to postmortem DWI in …

Tumor models and specific contrast agents for small animal imaging in oncology

Y Ni, H Wang, F Chen, J Li, F DeKeyzer, Y Feng, J Yu… - Methods, 2009 - Elsevier
Despite the widespread use of various imaging modalities in clinical and experimental
oncology without or with combined application of commercially available nonspecific …

The first study on therapeutic efficacies of a vascular disrupting agent CA4P among primary hepatocellular carcinomas with a full spectrum of differentiation and …

Y Liu, F De Keyzer, Y Wang, F Wang… - … Journal of Cancer, 2018 - Wiley Online Library
To better inform the next clinical trials of vascular disrupting agent combretastatin‐A4‐
phosphate (CA4P) in patients with hepatic malignancies, this preclinical study aimed at …

Use of non-invasive imaging to monitor response to aflibercept treatment in murine models of colorectal cancer liver metastases

KG Fleten, KM Bakke, GM Mælandsmo… - Clinical & experimental …, 2017 - Springer
The liver is the most frequent metastatic site in colorectal cancer (CRC), and relevant
orthotopic in vivo models are needed to study the efficacy of anticancer drugs in the …

Development, integration and use of an ultra-high-strength gradient system on a human-size 3 T magnet for small animal MRI

KH Cho, SM Huang, CH Choi, MJ Chen, HH Chiang… - PloS one, 2019 - journals.plos.org
This study aims to integrate an ultra-high-strength gradient coil system on a clinical 3 T
magnet and demonstrate its preclinical imaging capabilities. Dedicated phantoms were …

Early changes in apparent diffusion coefficients predict radiosensitivity of human nasopharyngeal carcinoma xenografts

J Pan, L Zang, Y Zhang, J Hong, Y Yao… - The …, 2012 - Wiley Online Library
Abstract Objectives/Hypothesis: Our objective was to predict the radiosensitivity of human
nasopharyngeal carcinoma xenografts in nude mice models through an examination of early …

Multi-modality bedding platform for combined imaging and irradiation of mice

J Müller, M Schürer, C Neubert, F Tillner… - Biomedical Physics …, 2020 - iopscience.iop.org
Preclinical imaging and irradiation yields valuable insights into clinically relevant research
topics. While complementary imaging methods such as computed tomography (CT) …

Imaging tumour-bearing animals using clinical scanners

G Wolf, N Abolmaali - International Journal of Radiation Biology, 2009 - Taylor & Francis
Purpose: We investigated the capability of small animal imaging in clinical scanners for
cancer research focusing on positron emission tomography (PET), computed tomography …