Psoriasis is a chronic inflammatory skin disease whose prevalence varies among different
populations worldwide. It is a complex multi-factorial disease and the exact etiology is …

Undisturbed epidermal differentiation is crucial for an intact skin barrier function. The
epidermal differentiation complex (EDC) is a cluster of genes on chromosome 1q21 …

BACKGROUND: Psoriasis and atopic dermatitis (AD) are common, complex inflammatory
skin diseases. Both diseases display immune infiltrates in lesions and epidermal …

There are clinical parallels between the nature and course of depressive symptoms in major
depressive disorder (MDD) and those of inflammatory disorders. However, the …

As chronic inflammatory conditions driven by immune dysregulation are influenced by
genetics and environment factors, psoriasis and atopic dermatitis (AD) have traditionally …

Loricrin is a terminally differentiating structural protein comprising more than 70% of the
cornified envelope. It contributes to the protective barrier function of the stratum corneum. In …

Psoriasis and psoriatic arthritis are multifactorial chronic disorders whose etiopathogenesis
essentially derives from the alteration of several signalling pathways and the co‐occurrence …

In the present study, we investigated the distribution of genetic variations in IL6 and IL6R
genes, which may be employed as prognostic and pharmacogenetic biomarkers for COVID …

Psoriasis is a common chronic inflammatory skin condition in which patients suffer from mild
to chronic plaque skin plaques. The disease manifests through an excessive inflammatory …

Psoriasis is a common inflammatory skin disease. It is known to be a complex condition with
multifactorial mode of inheritance, however the associations between particular pathogenic …