Drugs represent our first, and sometimes last, line of defense for many diseases, yet despite
decades of research we still do not fully understand why a given drug works in one patient …

Magnesium (Mg), an essential mineral abundantly present within the human body, is
intricately involved in a multitude of biochemical processes vital for maintaining health and …

Oral probiotics meet challenges during processing, storage, and gastrointestinal harsh
conditions. Polysaccharide‐based hydrogels delivery system is promising in probiotic …

Polysaccharides extracted from Hericium erinaceus (HEP) exhibit hepatoprotective activity
in the alleviation of non-alcoholic fatty liver disease (NAFLD); however, the mechanisms …

The gut microbiota is implicated in the pathogenesis of hyperuricemia (HUA) and gout.
However, it remains unclear whether probiotics residing in the host gut, such as …

The rising incidence of drug-induced liver injury (DILI) parallels contemporary dietary shifts
that have transformed the composition of human gut microbiota. The relationship between …

Cholestatic liver injury results from the accumulation of toxic bile acids in the liver,
presenting a therapeutic challenge with no effective treatment available to date …

Surface modification using biomaterials is crucial for constructing bioactive interfaces that
can control cell behavior, regulate biological processes, and interact with specific …

The mammalian gut microbiota plays diverse and essential roles in modulating host
physiology. Key mediators determining the outcome of the microbiota-host interactions are …

Extracellular histones have been determined as important mediators of sepsis, which induce
excessive inflammatory responses in macrophages and impair innate immunity. Magnesium …