The treatment of Cushing's disease

R Pivonello, M De Leo, A Cozzolino… - Endocrine …, 2015 - academic.oup.com
Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Cushing's syndrome

A Lacroix, RA Feelders, CA Stratakis, LK Nieman - The lancet, 2015 - thelancet.com
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's
syndrome, including debilitating morbidities and increased mortality. Genetic and molecular …

Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a double-blind, randomised withdrawal phase

R Pivonello, M Fleseriu, J Newell-Price… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Cushing's disease is a rare endocrine disorder characterised by cortisol
overproduction with severe complications. Therapies for cortisol reduction are often …

Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline

ME Wierman, W Arlt, R Basson, SR Davis… - The Journal of …, 2014 - academic.oup.com
Objective: To update practice guidelines for the therapeutic use of androgens in women.
Participants: A Task Force appointed by the Endocrine Society, American Congress of …

[HTML][HTML] A 12-month phase 3 study of pasireotide in Cushing's disease

A Colao, S Petersenn, J Newell-Price… - … England Journal of …, 2012 - Mass Medical Soc
Background Cushing's disease is associated with high morbidity and mortality. Pasireotide,
a potential therapy, has a unique, broad somatostatin-receptor–binding profile, with high …

The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics

E Valassi, A Santos, M Yaneva, M Tóth… - European journal of …, 2011 - academic.oup.com
Abstract Objective The European Registry on Cushing's syndrome (ERCUSYN) is designed
to collect prospective and follow-up data at EU level on Cushing's syndrome (CS). Design …

MANAGEMENT OF ENDOCRINE DISEASE: The burden of Cushing's disease: clinical and health-related quality of life aspects

RA Feelders, SJ Pulgar, A Kempel… - European journal of …, 2012 - academic.oup.com
Objective Cushing's disease (CD) is a rare endocrine disorder characterized by excess
secretion of ACTH due to a pituitary adenoma. Current treatment options are limited and …

Neuropsychiatric disorders in Cushing's syndrome

R Pivonello, C Simeoli, MC De Martino… - Frontiers in …, 2015 - frontiersin.org
Endogenous Cushing's syndrome (CS), a rare endocrine disorder characterized by cortisol
hypersecretion, is associated with psychiatric and neurocognitive disorders. Major …

Outcome of bilateral adrenalectomy in Cushing's syndrome: a systematic review

K Ritzel, F Beuschlein, A Mickisch… - The Journal of …, 2013 - academic.oup.com
Background: The outcome of bilateral adrenalectomy (BADx) in patients with Cushing's
syndrome (CS) is not well characterized. Methods: A literature search was performed with …

Hypercoagulability in C ushing's syndrome: prevalence, pathogenesis and treatment

R van der Pas, FWG Leebeek, LJ Hofland… - Clinical …, 2013 - Wiley Online Library
Cushing's syndrome is not only accompanied by an increased prevalence of cardiovascular
disease but also by a hypercoagulable state that is reflected by an increased incidence of …