Challenges and opportunities for brainstem neuroimaging with ultrahigh field MRI

R Sclocco, F Beissner, M Bianciardi, JR Polimeni… - Neuroimage, 2018‏ - Elsevier
The human brainstem plays a central role in connecting the cerebrum, the cerebellum and
the spinal cord to one another, hosting relay nuclei for afferent and efferent signaling, and …

State-of-the-art imaging of neuromodulatory subcortical systems in aging and Alzheimer's disease: Challenges and opportunities

N Engels-Domínguez, EA Koops, PC Prokopiou… - Neuroscience & …, 2023‏ - Elsevier
Primary prevention trials have shifted their focus to the earliest stages of Alzheimer's disease
(AD). Autopsy data indicates that the neuromodulatory subcortical systems'(NSS) nuclei are …

[HTML][HTML] SANDI: A compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

M Palombo, A Ianus, M Guerreri, D Nunes… - Neuroimage, 2020‏ - Elsevier
This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

PAM50: Unbiased multimodal template of the brainstem and spinal cord aligned with the ICBM152 space

B De Leener, VS Fonov, DL Collins, V Callot, N Stikov… - Neuroimage, 2018‏ - Elsevier
Template-based analysis of multi-parametric MRI data of the spinal cord sets the foundation
for standardization and reproducibility, thereby hel** the discovery of new biomarkers of …

Integrating brainstem and cortical functional architectures

JY Hansen, S Cauzzo, K Singh… - Nature …, 2024‏ - nature.com
The brainstem is a fundamental component of the central nervous system, yet it is typically
excluded from in vivo human brain map** efforts, precluding a complete understanding of …

High‐resolution in vivo diffusion imaging of the human brain with generalized slice dithered enhanced resolution: Simultaneous multislice (g S lider‐SMS)

K Setsompop, Q Fan, J Stockmann… - Magnetic resonance …, 2018‏ - Wiley Online Library
Purpose To develop an efficient acquisition for high‐resolution diffusion imaging and allow
in vivo whole‐brain acquisitions at 600‐to 700‐μm isotropic resolution. Methods We …

Neuromodulatory subcortical nucleus integrity is associated with white matter microstructure, tauopathy and APOE status

A Wearn, SA Tremblay, CL Tardif, IR Leppert… - Nature …, 2024‏ - nature.com
The neuromodulatory subcortical nuclei within the isodendritic core (IdC) are the earliest
sites of tauopathy in Alzheimer's disease (AD). They project broadly throughout the brain's …

Racial discrimination, neural connectivity, and epigenetic aging among black women

A Elbasheir, S Katrinli, BE Kearney… - JAMA Network …, 2024‏ - jamanetwork.com
Importance Racial discrimination increases the risk of adverse brain health outcomes,
potentially via neuroplastic changes in emotion processing networks. The involvement of …

The structural connectivity map** of the intralaminar thalamic nuclei

VJ Kumar, K Scheffler, W Grodd - Scientific Reports, 2023‏ - nature.com
The intralaminar nuclei of the thalamus play a pivotal role in awareness, conscious
experience, arousal, sleep, vigilance, as well as in cognitive, sensory, and sexual …

Distortion‐free, high‐isotropic‐resolution diffusion MRI with gSlider BUDA‐EPI and multicoil dynamic B0 shimming

C Liao, B Bilgic, Q Tian, JP Stockmann… - Magnetic resonance …, 2021‏ - Wiley Online Library
Purpose We combine SNR‐efficient acquisition and model‐based reconstruction strategies
with newly available hardware instrumentation to achieve distortion‐free in vivo diffusion …