Spindle assembly and chromosome dynamics during oocyte meiosis
Organisms that reproduce sexually utilize a specialized form of cell division called meiosis to
reduce their chromosome number by half to generate haploid gametes. Meiosis in females …
reduce their chromosome number by half to generate haploid gametes. Meiosis in females …
Kinetochore component function in C. elegans oocytes revealed by 4D tracking of holocentric chromosomes
L Pitayu-Nugroho, M Aubry, K Laband… - Nature …, 2023 - nature.com
During cell division, chromosome congression to the spindle center, their orientation along
the spindle long axis and alignment at the metaphase plate depend on interactions between …
the spindle long axis and alignment at the metaphase plate depend on interactions between …
Parts list for a microtubule depolymerising kinesin
CT Friel, JP Welburn - Biochemical Society Transactions, 2018 - portlandpress.com
The Kinesin superfamily is a large group of molecular motors that use the turnover of ATP to
regulate their interaction with the microtubule cytoskeleton. The coupled relationship …
regulate their interaction with the microtubule cytoskeleton. The coupled relationship …
Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis
MM Shan, YJ Zou, ZN Pan, HL Zhang, Y Xu… - …, 2022 - journals.biologists.com
Mammalian oocyte maturation is a unique asymmetric division, which is mainly because of
actin-based spindle migration to the cortex. In the present study, we report that a kinesin …
actin-based spindle migration to the cortex. In the present study, we report that a kinesin …
Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
In the Caenorhabditis elegans germline, thousands of mRNAs are concomitantly expressed
with antisense 22G-RNAs, which are loaded into the Argonaute CSR-1. Despite their …
with antisense 22G-RNAs, which are loaded into the Argonaute CSR-1. Despite their …
Evidence for anaphase pulling forces during C. elegans meiosis
BM Danlasky, MT Panzica, KP McNally, E Vargas… - Journal of Cell …, 2020 - rupress.org
Anaphase chromosome movement is thought to be mediated by pulling forces generated by
end-on attachment of microtubules to the outer face of kinetochores. However, it has been …
end-on attachment of microtubules to the outer face of kinetochores. However, it has been …
A degron-based strategy reveals new insights into Aurora B function in C. elegans
The widely conserved kinase Aurora B regulates important events during cell division.
Surprisingly, recent work has uncovered a few functions of Aurora-family kinases that do not …
Surprisingly, recent work has uncovered a few functions of Aurora-family kinases that do not …
Synergistic stabilization of microtubules by BUB-1, HCP-1, and CLS-2 controls microtubule pausing and meiotic spindle assembly
During cell division, chromosome segregation is orchestrated by a microtubule-based
spindle. Interaction between spindle microtubules and kinetochores is central to the bi …
spindle. Interaction between spindle microtubules and kinetochores is central to the bi …
BUB-1 and CENP-C recruit PLK-1 to control chromosome alignment and segregation during meiosis I in C. elegans oocytes
SJP Taylor, LB Borja, F Soubigou, J Houston… - Elife, 2023 - elifesciences.org
Phosphorylation is a key post-translational modification that is utilised in many biological
processes for the rapid and reversible regulation of protein localisation and activity. Polo-like …
processes for the rapid and reversible regulation of protein localisation and activity. Polo-like …
The doublecortin-family kinase ZYG-8DCLK1 regulates microtubule dynamics and motor-driven forces to promote the stability of C. elegans acentrosomal spindles
Although centrosomes help organize spindles in most cell types, oocytes of most species
lack these structures. During acentrosomal spindle assembly in C. elegans oocytes …
lack these structures. During acentrosomal spindle assembly in C. elegans oocytes …