Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

S Bindu, S Mazumder, U Bandyopadhyay - Biochemical pharmacology, 2020 - Elsevier
Owing to the efficacy in reducing pain and inflammation, non-steroidal anti-inflammatory
drugs (NSAIDs) are amongst the most popularly used medicines confirming their position in …

Chronic inflammation in the etiology of disease across the life span

D Furman, J Campisi, E Verdin, P Carrera-Bastos… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

Leaky gut: mechanisms, measurement and clinical implications in humans

M Camilleri - Gut, 2019 - gut.bmj.com
The objectives of this review on 'leaky gut'for clinicians are to discuss the components of the
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …

[HTML][HTML] A gut microbiota-bile acid axis promotes intestinal homeostasis upon aspirin-mediated damage

T Li, N Ding, H Guo, R Hua, Z Lin, H Tian, Y Yu… - Cell Host & Microbe, 2024 - cell.com
Aspirin-related gastrointestinal damage is of growing concern. Aspirin use modulates the gut
microbiota and associated metabolites, such as bile acids (BAs), but how this impacts …

Lessons from 20 years with COX‐2 inhibitors: Importance of dose–response considerations and fair play in comparative trials

CO Stiller, P Hjemdahl - Journal of internal medicine, 2022 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) inhibit the enzyme cyclooxygenase (COX),
which forms prostaglandins involved in pain and inflammation. COX inhibitors have …

Defining high bleeding risk in patients undergoing percutaneous coronary intervention: a consensus document from the Academic Research Consortium for High …

P Urban, R Mehran, R Colleran… - European heart …, 2019 - academic.oup.com
Identification and management of patients at high bleeding risk undergoing percutaneous
coronary intervention are of major importance, but a lack of standardization in defining this …

Lactobacillus reuteri maintains intestinal epithelial regeneration and repairs damaged intestinal mucosa

H Wu, S **e, J Miao, Y Li, Z Wang, M Wang, Q Yu - Gut microbes, 2020 - Taylor & Francis
Little is known about the regulatory effect of microbiota on the proliferation and regeneration
of ISCs. Here, we found that L. reuteri stimulated the proliferation of intestinal epithelia by …

[HTML][HTML] Akkermansia muciniphila and Faecalibacterium prausnitzii in Immune-Related Diseases

RMRA Effendi, M Anshory, H Kalim, RF Dwiyana… - Microorganisms, 2022 - mdpi.com
Probiotics and synbiotics are used to treat chronic illnesses due to their roles in immune
system modulation and anti-inflammatory response. They have been shown to reduce …

[HTML][HTML] An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia

T Van De Donk, M Niesters, MA Kowal, E Olofsen… - Pain, 2019 - journals.lww.com
In this experimental randomized placebo-controlled 4-way crossover trial, we explored the
analgesic effects of inhaled pharmaceutical-grade cannabis in 20 chronic pain patients with …