ctGAN: combined transformation of gene expression and survival data with generative adversarial network

J Kim, J Seok - Briefings in Bioinformatics, 2024 - academic.oup.com
Recent studies have extensively used deep learning algorithms to analyze gene expression
to predict disease diagnosis, treatment effectiveness, and survival outcomes. Survival …

Leveraging methylation alterations to discover potential causal genes associated with the survival risk of cervical cancer in TCGA through a two-stage inference …

J Zhang, H Lu, S Zhang, T Wang, H Zhao… - Frontiers in …, 2021 - frontiersin.org
Background Multiple genes were previously identified to be associated with cervical cancer;
however, the genetic architecture of cervical cancer remains unknown and many potential …

Prioritizing Disease Diagnosis in Neonatal Cohorts through Multivariate Survival Analysis: A Nonparametric Bayesian Approach

J Seo, J Seok, Y Kim - Healthcare, 2024 - mdpi.com
Understanding the intricate relationships between diseases is critical for both prevention
and recovery. However, there is a lack of suitable methodologies for exploring the …

How can gene-expression information improve prognostic prediction in TCGA cancers: an empirical comparison study on regularization and mixed cox models

X Yu, T Wang, S Huang, P Zeng - Frontiers in Genetics, 2020 - frontiersin.org
Background Previous cancer prognostic prediction models often consider only the most
important transcriptomic expressions, and their power is limited. It is unknown whether …

CTIVA: Censored time interval variable analysis

I Kim, J Seok, Y Kim - Plos one, 2023 - journals.plos.org
Traditionally, datasets with multiple censored time-to-events have not been utilized in
multivariate analysis because of their high level of complexity. In this paper, we propose the …

Prediction of survival risks with adjusted gene expression through risk-gene networks

M Lee, SW Han, J Seok - Bioinformatics, 2019 - academic.oup.com
Motivation Network-based analysis of biomedical data has been extensively studied over
the last decades. As a successful application, gene networks have been used to illustrate …